Protein Alignment inaE and Daglb

DIOPT Version :10

• Sequence 1: NP_001138195.1
• Gene: inaE / 32343
• FlyBaseID: FBgn0261244
• Length: 1318
• Species: Drosophila melanogaster
• Sequence 2: NP_659164.2
• Gene: Daglb / 231871
• MGIID: 2442032
• Length: 669
• Species: Mus musculus
• Alignment Length: 711
• Identity: 241/711 - (33%)
• Similarity: 376/711 - (52%)
• Gaps: 81/711 - (11%)

  Fly     1 MPGLVVFRRRWSVGSDDLVVPGAFLLTIHFICFVIVSVSLVIFEYNTRILSVK---LLFYHLIGY 62
            |||:|:|.||||:.|||||.||:|.|.:..:.::   |||.::..:.|.|...   ||..:||..
Mouse     1 MPGMVLFGRRWSLASDDLVFPGSFELFLRVLWWI---VSLTLYLTHRRRLDCPGGVLLSTYLIVL 62

  Fly    63 LLILFFSICVEIGICVISMRGSILDAEARTSINIWIYLKSLVILFDIAWLAVGSVWLGHYYTTAP 127
            |::|...||..:.|..:||||:|.:...|.|::..:|::..:.|.::.|.::|:.|:     ...
Mouse    63 LVLLAVIICTVLAIVCVSMRGTICNPGPRKSMSKLLYIRLALFLPEMVWASLGAAWV-----AKG 122

  Fly   128 IDDPKKVYIAII---ICNWALVVITLITIWCTFDAAGRSWVKMKKYQRSMRETESRFNYKRSNSM 189
            |...:.|.|.||   |.:|.::..|::||...||..|.   ||..|...:.|      :..|||.
Mouse   123 IQCDRTVVIGIIATVIVSWIVIAATMVTIIFVFDPLGG---KMAPYPPCIPE------HLDSNSS 178

  Fly   190 NRNWRQRKVMRAYQDSWDHRCRLLFCCMGSSERNRNSFTDIARLLSDFFRELDVVPSDVVAGLVL 254
            ||.....|.  |.:..|:.|.:...||:|..:..|.:|:..|.|.|.:|.:.|:||||:.||..|
Mouse   179 NRLLTGLKT--AAKSVWETRVQFCCCCVGQDDNTRVAFSSTADLFSTYFSDTDLVPSDIAAGFTL 241

  Fly   255 LRKFQRLEREAIVRQRKNGTYEFLSGVP-ITERTQFLALNDAKNYDFFQTVIHYMYFAQGAYGWP 318
            |.:    :::.|...|:  ..|.::..| ..:.|:.    ||:    .:...|||.||..|||||
Mouse   242 LHQ----QQDNISHSRE--PPEVVTHTPGQPQETEL----DAE----VENCHHYMPFAAAAYGWP 292

  Fly   319 MYVIINRSKMWHLVPELKCFGCCCGTSD-DTEVIQDNCCLCNYAALKKTLQLGDIDIVYATYHVD 382
            :|:..|     ......:..|.||...| :.:.::.:...|::|::.||..|...|.::.::|..
Mouse   293 LYIYRN-----PFTGLCRIGGDCCRARDIEYDAVEGDQHNCHFASILKTTGLQYRDFIHISFHDK 352

  Fly   383 VGETPFFVAIDYTHRAVVISIRGTLSMKDILTDLNAEGEVLPLQPPRDDWLGHKGMVQAAIYIRN 447
            |.|.||.|.:|:...:||:::|||:|::|:||||:||.|.|.|.....|.:.|||:.|||.||..
Mouse   353 VYELPFIVVLDHRKESVVVAVRGTMSLQDVLTDLSAESETLELGIELQDCVAHKGIAQAARYIHR 417

  Fly   448 KLQEENLIERALQRNPDRQTHTFDLVLVGHSLGAGTAAILAILLKPEHPTLQCFSYSPPGGLLSM 512
            :|..:.::.:|....|:     :.|||||||||||.||:|||:|:..:|.::.:::|||.||||.
Mouse   418 RLVNDGILSQAFSVAPE-----YQLVLVGHSLGAGAAALLAIMLRGAYPQVRAYAFSPPRGLLSK 477

  Fly   513 PAVEYSKSFITSVVLGKDVVPRIGLNQMEALRADLINAIQRSVDPKWKTI--SCSVICCGCGPE- 574
            ...||||.|:.|::||.||:||:.:..||.|:..::..|.....||:|.:  .|.....|..|:
Mouse   478 SLYEYSKDFVVSLILGMDVIPRLSVTNMEDLKRRILRVIANCNKPKYKILLHGCWYGLFGGSPDN 542

  Fly   575 -PTSVVN---------MSGQDTHINQYQEERGTARSTSAHPTDSSIALTLHQPLYPPGRIIHIVR 629
             ||.:..         :.|:.|.:.:|..  |...|.|  |.||.   |.:..|||||||||:
Mouse   543 FPTELDEGTQGALTQPLLGEQTLLTRYSP--GYCSSDS--PLDSP---TKYPTLYPPGRIIHL-- 598

  Fly   630 HHPKPDEQKYDSGWRNVLKNREPVYQAIWADSTDFDEVLISPVMLQDHMPDKVLAALKKVV 690
                  |::..||........:  |:|.||...:|.::||.|.||.|||||.::.||.:|:
Mouse   599 ------EEEGGSGRFGCCSAAQ--YRARWAHEAEFSKILIGPKMLIDHMPDVMIRALDRVL 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaE	NP_001138195.1	Lipase_3	300..542	CDD:238287	95/242 (39%)
Daglb	NP_659164.2	Lipase_3	274..507	CDD:238287	95/246 (39%)