Protein Alignment CtsB and ctsf

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001071036.2
• Gene: ctsf / 565588
• ZFINID: ZDB-GENE-030131-9831
• Length: 473
• Species: Danio rerio
• Alignment Length: 345
• Identity: 73/345 - (21%)
• Similarity: 130/345 - (37%)
• Gaps: 94/345 - (27%)

  Fly     9 TAASVAALTSGE--------PSLLSDEFIEVVRSKAKTWTVGRNFDASVTEGHIRRLMGVHPDAH 65
            ||.::.:|..|.        ..|..|||                           |:|.::|...
Zfish   205 TAQTLQSLEQGSAEYGITKFSDLTEDEF---------------------------RMMYLNPMLS 242

  Fly    66 KFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCI 130
            :::|  |:|:...:..::  ..|:.:|    |.:...:..:::||.|||||||.....:..:...
Zfish   243 QWSL--KKEMKPAIPASA--PAPDTWD----WRDHGAVSPVKNQGMCGSCWAFSVTGNIEGQWFK 299

  Fly   131 HSGGKVNFHFSADDLVSCCHTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEH 195
            .:|..::  .|..:||. |......|.||.|..|:......|.:.
Zfish   300 KTGQLLS--LSEQELVD-CDKLDQACGGGLPSNAYEAIENLGGLE-------------------- 341

  Fly   196 HVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDK--HFGSKSYSVRRNVREIQEEIMTNGPVEGA 258
                |....::.|....|          |::..|  .:.:.|..:.::.:||...:..||||..|
Zfish   342 ----TETDYSYTGHKQSC----------DFSTGKVAAYINSSVELPKDEKEIAAFLAENGPVSAA 392

  Fly   259 FTVYEDLILYKDGVYQHEH------GKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGF 317
            ...:. :..|:.||   .|      ...:..||:.::|:|  ....:|:|.|.|||..|:|:.|:
Zfish   393 LNAFA-MQFYRKGV---SHPLKIFCNPRMIDHAVLLVGFG--QRNGVPFWAIKNSWGEDYGEQGY 451

  Fly   318 FRILRGQDHCGIESSISAGL 337
            :.:.||...|||....|:.:
Zfish   452 YYLYRGSGLCGIHKMCSSAI 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	6/39 (15%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	59/255 (23%)
ctsf	NP_001071036.2	None