Protein Alignment CtsB and zgc:110239

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001017633.2
• Gene: zgc:110239 / 550326
• ZFINID: ZDB-GENE-050417-107
• Length: 546
• Species: Danio rerio
• Alignment Length: 320
• Identity: 81/320 - (25%)
• Similarity: 124/320 - (38%)
• Gaps: 68/320 - (21%)

  Fly    28 FIEVVRSKAKTWTVGRNFDASVTE---------GHIRRLMGVHPDAHKFALPDKREVLGDLYVNS 83
            |:..:|........|.:|..||..         ..:|.....| ..|:.|.|...|:......||
Zfish   267 FVHNIRYVHSMNRAGLSFSLSVNHLADRSQKELSMMRGCQRTH-KVHRKAQPFPSEIRSIATPNS 330

  Fly    84 VDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSC 148
            ||           |.....:..::||..|||||:|.....:...:.:.:|...:  .|...||.|
Zfish   331 VD-----------WRLYGAVTPVKDQAVCGSCWSFATTGTLEGALFLKTGQLTS--LSQQMLVDC 382

  Fly   149 CHTCGFGCNGGFPGAAWS--YWTRK--GIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGR 209
              |.|||.||...|..|.  .|..|  ||.:...||:..|            :||.   |.:
Zfish   383 --TWGFGNNGCDGGEEWRAFEWIMKHGGISTAESYGAYMG------------MNGL---CHY--- 427

  Fly   210 TPKCSHVCQ-SGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAF-TVYEDLILYKDGV 272
             .|.|.|.| :|||...:.|             :..::..|...|||..:. ..:.....|.:||
Zfish   428 -DKTSMVAQLTGYTNVTSGD-------------ILALKAAIFKFGPVAVSIDAAHRSFAFYSNGV 478

  Fly   273 Y---QHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGI 329
            |   :.::|.....||:..:|:|:...|.  |||:.|||::.||:.|:..:....::||:
Zfish   479 YYEPECKNGINDLDHAVLAVGYGIMNNES--YWLVKNSWSSYWGNDGYILMSMKDNNCGV 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	8/44 (18%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	65/251 (26%)
zgc:110239	NP_001017633.2	Inhibitor_I29	243..298	CDD:214853	6/30 (20%)
		Peptidase_C1A	328..543	CDD:239068	69/258 (27%)