Protein Alignment CtsB and CtsL4

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_609387.1
• Gene: CtsL4 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 330
• Identity: 74/330 - (22%)
• Similarity: 126/330 - (38%)
• Gaps: 87/330 - (26%)

  Fly    26 DEFIEVVRSKAKTWTVGRN--------FDASVTEGHIR---RLM--GVHPDAHKFALPDKREVLG 77
            :|..:|:....:.:..|:.        |....|:|:::   ||:  .:...|...|     |::|
  Fly    61 EENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMA-----EIVG 120

  Fly    78 DLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSA 142
            ...:.:|   ||..|.|.:....|...::    |||||:||...|::..:| ....||: ...|.
  Fly   121 SPLMANV---PESLDWRSKGFITPPYNQL----SCGSCYAFSIAESIMGQV-FKRTGKI-LSLSK 176

  Fly   143 DDLVSCCHTCG-FGCNGGFPGAAWSYWTRKGIV---SGGPYGSNQGCRPYEISPCEHHVNGTRPP 203
            ..:|.|..:.| .||.||......||....|.:   ...||.:.:|       .|:.
  Fly   177 QQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARKG-------KCQF-------- 226

  Fly   204 CAHGGRTPKCSHVCQSGYTVDYAKDK--------HFGSKSYSVRRNVREIQEEIMTNGPVEGAFT 260
                  .|..|.|..:.:.:...:|:        |.|..:.|:..:.:..|
  Fly   227 ------VPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQ-------------- 271

  Fly   261 VYEDLILYKDGVYQHEHGKELG-GHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQ 324
                  ||.||:|......... .||:.::|:|.      .||::.|.|..:||::|:.||.:|.
  Fly   272 ------LYSDGIYDDPLCSSASVNHAMVVIGFGK------DYWILKNWWGQNWGENGYIRIRKGV 324

  Fly   325 DHCGI 329
            :.|||
  Fly   325 NMCGI 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	8/50 (16%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	61/255 (24%)
CtsL4	NP_609387.1	Inhibitor_I29	36..96	CDD:462410	5/34 (15%)
		Peptidase_C1A	128..336	CDD:239068	61/255 (24%)