Protein Alignment CtsB and Y113G7B.15

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_507904.2
• Gene: Y113G7B.15 / 190976
• WormBaseID: WBGene00013764
• Length: 362
• Species: Caenorhabditis elegans
• Alignment Length: 348
• Identity: 95/348 - (27%)
• Similarity: 142/348 - (40%)
• Gaps: 88/348 - (25%)

  Fly    29 IEVVRSKAKTWTVGRNFDASVTEGHIR-----------RLMGVHPDAHKFALP------------ 70
            |:.:.:||:  ..|||    ||.|..:           |...:||..|. .||
 Worm    61 IQELNAKAR--REGRN----VTFGWNKFADKNRQELSARNSKIHPKNHT-DLPIYKPRHPRGSRN 118

  Fly    71 -----DKREVLGDLYVNSVDELPEEFDSRKQW-PNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVC 129
                 .||: .||        :|:.||.|..: ...|.:|.::||..||.||||...........
 Worm   119 HHNKRSKRQ-SGD--------IPDYFDLRDIYVDGSPVVGPVKDQEQCGCCWAFATTAITEAANT 174

  Fly   130 IHSGGKVNFHFSADDLVSCCHTCGF--GCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISP 192
            ::|   .:|...:|..:..|...|.  ||.||.|.........:|..|.|.|       |||
 Worm   175 LYS---KSFTSLSDQEICDCADSGDTPGCVGGDPRNGLKMVHLRGQSSDGDY-------PYE--- 226

  Fly   193 CEHHVNGTRPPCAHGGRT----PKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNG 253
             |:..| |...|....::    |:..:|.:  :..|||::               :|.|.:..|.
 Worm   227 -EYRAN-TTGNCVGDEKSTVIQPETLNVYR--FDQDYAEE---------------DIMENLYLNH 272

  Fly   254 -PVEGAFTVYEDLILYKDGVYQHEHGKEL---GGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGD 314
             |....|.|.|:...|..||.|.|...::   ..|::.|:|:|. .::.:||||:.||||:|||.
 Worm   273 IPTAVYFRVGENFEWYTSGVLQSEDCYQMTPAEWHSVAIVGYGT-SDDGVPYWLVRNSWNSDWGL 336

  Fly   315 HGFFRILRGQDHCGIESSISAGL 337
            ||:.:|.||.:.|.|||..:..:
 Worm   337 HGYVKIRRGVNWCLIESHAATAM 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	12/45 (27%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	76/258 (29%)
Y113G7B.15	NP_507904.2	Inhibitor_I29	30..90	CDD:462410	9/34 (26%)
		Peptidase_C1A	132..358	CDD:239068	76/258 (29%)