Protein Alignment CtsB and ctss.3

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_017952033.2
• Gene: ctss.3 / 105948322
• XenbaseID: XB-GENE-29089987
• Length: 337
• Species: Xenopus tropicalis
• Alignment Length: 341
• Identity: 83/341 - (24%)
• Similarity: 135/341 - (39%)
• Gaps: 98/341 - (28%)

  Fly    30 EVVRSKAKTWTVGRNFDASVTEGHIRRLMGVHPDAHKFALPDKREV----LGDLYVNSVDE---- 86
            |..|::...|.....|   :|..::...:|:|          ..||    |||:   :|||
 Frog    45 EEERARRTIWEETLKF---ITVHNLEYSLGLH----------TYEVGMNHLGDM---TVDEFTAT 93

  Fly    87 -------------------------LPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSD 126
                                     :|.|.|.|::  .|.|  :::.||.||||:||.|:.||..
 Frog    94 MSGFKASDDPVPNVTYVPIRGMKRTIPHEIDWREK--GCVT--DVKSQGKCGSCYAFSALGAMEG 154

  Fly   127 RVCIHSGGKVNFHFSADDLVSCCHTCG-FGCNGGFPGAAWSYWTRKGIVSGG--PYGSNQGCRPY 188
            :....|...|:  .|..::|.|....| .||..|....::.|....|:.|..  ||.:.:|.:.|
 Frog   155 QWQEWSEELVS--LSEQNIVDCSRDYGNSGCKDGTITGSFEYIKDHGVASESSYPYKAQEGAKCY 217

  Fly   189 EISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNG 253
             ::|                 ..|..| |:....:::..::|              :.|.:.|.|
 Frog   218 -LNP-----------------NAKTFH-CKGYKEIEHQNEEH--------------LMEVVGTIG 249

  Fly   254 PVEGAF-TVYEDLILYKDGVYQHEHGKELGG---HAIRILGWGVWGEEKIPYWLIGNSWNTDWGD 314
            ||..|. ..::....|.:|||.::......|   ||:.::|:|  .|:...|||:.||....|||
 Frog   250 PVAVAIDATHDGFKYYTNGVYTNDKCNNSNGGQKHAVLVVGYG--REDGKDYWLVKNSNGPGWGD 312

  Fly   315 HGFFRILRG-QDHCGI 329
            .|:.::.|. .:||||
 Frog   313 KGYIKMRRNYSNHCGI 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	7/33 (21%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	68/250 (27%)
ctss.3	XP_017952033.2	Inhibitor_I29	30..89	CDD:214853	13/59 (22%)
		Peptidase_C1A	120..335	CDD:239068	68/250 (27%)