Protein Alignment Neto and Neto2

DIOPT Version :10

• Sequence 1: NP_001285211.1
• Gene: Neto / 32303
• FlyBaseID: FBgn0265416
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001100887.2
• Gene: Neto2 / 307757
• RGDID: 1305310
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 136/496 - (27%)
• Similarity: 223/496 - (44%)
• Gaps: 88/496 - (17%)

  Fly   138 RCRLFVEGDPTKN--ELYSPEYPNLYPKNINCTRVITAPKGQIIRLDFRNSFNIEAKEGCKFDFL 200
            :|.::|.   |.|  ...||.||:.||.|..|..::.|...|.|.|.|...:.||....|:||.|
  Rat    44 QCGIWVR---TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDERYYIEPSFECRFDHL 105

  Fly   201 EIRDGQYGFSTLIGKFCGTDFPPEITSKERYLWLHFHSDETIEYTGFSAVYEYLDRSRDAPSTDL 265
            |:|||.:|||.||.::||...|..|.|..|::|:.|.|||.:|..||.|.|.::      |..|.
  Rat   106 EVRDGPFGFSPLIDRYCGMKSPALIRSTGRFMWIKFSSDEELEGLGFRAKYSFI------PDPDF 164

  Fly   266 -----------NCTIDKGGFEGFINSTDVPAEIWEQVNRNK--IALDCIWRIQVKENWKIFLKFL 317
                       :|..:..|.:|.:.|:.|     ||..:.|  .|:||||.|:.....||:|:||
  Rat   165 TYLGGILNPIPDCQFELSGADGIVRSSQV-----EQEEKTKPGQAVDCIWTIKATPKAKIYLRFL 224

  Fly   318 DFKLSKPNDCQTNFLDIFPEQTVMPLRVKNFCGSAGESITAESNILHLRFYADQTAINSTFGILF 382
            |:::...|:|:.||:.::...:.:......||.:....:..::.:..:|.:||:.:..|.|.:||
  Rat   225 DYQMEHSNECKRNFVAVYDGSSAIENLKAKFCSTVANDVMLKTGVGVIRMWADEGSRLSRFRMLF 289

  Fly   383 TAFRERGAACTEDEYDCEDATCISKDLKCNNLDNCKFRWDEEGC-TSEAAGQSE-----HVVIIV 441
            |:|.|  ..||...:.|....||:..|.||.:.||.:.|||..| ..:.||..|     |..||.
  Rat   290 TSFVE--PPCTSSTFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGLFEQITKTHGTIIG 352

  Fly   442 IVFGLILGGMVITFIVNC---IRKI-------------------------IRDQKIIREHIRESK 478
            :..|::|..::|:.:|..   .:|:                         :|:::|..:....|:
  Rat   353 VTSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLREKEISADLADLSE 417

  Fly   479 ESKLDEMGRNSKGRSR--------ENISRQKHSQTSLQILDDVSNRYYREAVPLSSQSSKADFKE 535
            |....:..|.|...||        ...|..|.|:|:|..::......:.:..|:.:.:|  .||:
  Rat   418 ELDNYQKLRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRNDFAQPQPMKTFNS--TFKK 480

  Fly   536 KEHSILRRHADMTQTSL---------CGV---GEDDGESSS 564
            ..::..:.| |..:.:|         |.:   |.||...:|
  Rat   481 SSYTFKQTH-DCPEQALEDRVMEEIPCEIYVRGRDDSAQAS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neto	NP_001285211.1	CUB	151..252	CDD:238001	43/100 (43%)
		CUB	<298..384	CDD:238001	24/85 (28%)
		LDLa	392..426	CDD:238060	13/33 (39%)
Neto2	NP_001100887.2	CUB	45..158	CDD:238001	48/115 (42%)
		CUB	<205..291	CDD:238001	24/85 (28%)
		LDLa	297..331	CDD:238060	13/33 (39%)