Protein Alignment Neto and neto2b

DIOPT Version :10

• Sequence 1: NP_001285211.1
• Gene: Neto / 32303
• FlyBaseID: FBgn0265416
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: XP_021323426.1
• Gene: neto2b / 100034584
• ZFINID: ZDB-GENE-060503-638
• Length: 537
• Species: Danio rerio
• Alignment Length: 514
• Identity: 141/514 - (27%)
• Similarity: 220/514 - (42%)
• Gaps: 98/514 - (19%)

  Fly   154 SPEYPNLYPKNINCTRVITAPKGQIIRLDFRNSFNIEAKEGCKFDFLEIRDGQYGFSTLIGKFCG 218
            ||.||:.||.|..|..::.|...:.|:|.|.:.::||....|:||.:|||||.:.||.||.:|||
Zfish    53 SPNYPSTYPPNKECVYILEAHPRKRIQLVFDDIYHIEPSFECRFDNIEIRDGPFIFSPLINRFCG 117

  Fly   219 TDFPPEITSKERYLWLHFHSDETIEYTGFSAVYEYLDRSRDAPSTDL----------NCTIDKGG 273
            ...|..:||..|:||:.|.|||.:|..||...|.|   :.| |...|          :|..:..|
Zfish   118 DKSPGIVTSSGRFLWIKFTSDEELEELGFKVEYSY---TAD-PDFHLHVGGLLNPIPDCQFEMSG 178

  Fly   274 FEGFINSTDVPAEIWEQVNRNKI----ALDCIWRIQVKENWKIFLKFLDFKLSKPNDCQTNFLDI 334
            .:|.|.|:.|..|       ||:    |:||||.|:.....||:|:|||::|...|:|:.||:.:
Zfish   179 ADGVIRSSQVEEE-------NKVKAGEAVDCIWTIRAPPMSKIYLRFLDYQLENSNECKKNFVAV 236

  Fly   335 FP-EQTVMPLRVKNFCGSAGESITAESNILHLRFYADQTAINSTFGILFTAFRERGAACTEDEYD 398
            :. ...:..|:.| ||.:....||.::.:..:|.:||:|:..|.|.:|||.|.|  ..|:.:.|.
Zfish   237 YEGSNAIEDLKAK-FCSTVANDITLDNTVAVVRMWADETSKLSRFRLLFTVFTE--PPCSPNAYF 298

  Fly   399 CEDATCISKDLKCNNLDNCKFRWDEEGCTSEAAG------QSEHVVIIVIVFGLILGGMVITFIV 457
            |....||:..|.||.:.||.|.|||..|..:...      ...|..:|.:..|::...::|:..:
Zfish   299 CHSNMCINNTLVCNGVQNCVFPWDENNCREKKPKTFFHQMSKTHGTVIGVSTGVVCLLLIISIFI 363

  Fly   458 NCIRKIIRDQKIIREHI--------------------------RESKESKLDEMGRNSKGRSREN 496
            .  .|..|.:.:.|:.:                          .|..|.:|:.:.:..:..|...
Zfish   364 Q--MKQPRKKILCRKGLFSATEMQEVMDPPEYEMFSMQDTDMPEELLEEELEGLQKLHRSASMSR 426

  Fly   497 ISRQKH--SQTSLQILDDVSNRYYREAVPLSSQSSKADFKEKEHSILRRHADMTQTSLCGVGEDD 559
            ..|:.|  :..|..||...:|       |||.:.|                  |.......|...
Zfish   427 CIREHHCGAHNSTTILMTRTN-------PLSEELS------------------TAVGARSWGSFH 466

  Fly   560 GESSSTTT---ATHEMMTKAAMSAVPSNACDMGCQTRESLFVNSPGIGPSAGPGVGVAV 615
            |..||:.:   .||....::...|:..:...:..|..|.:     |.....|.|.||.:
Zfish   467 GRRSSSRSHHPHTHAYSAQSLREALEEDELSLEGQVMEEI-----GYNEVFGRGRGVVM 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neto	NP_001285211.1	CUB	151..252	CDD:238001	42/97 (43%)
		CUB	<298..384	CDD:238001	30/86 (35%)
		LDLa	392..426	CDD:238060	14/33 (42%)
neto2b	XP_021323426.1	CUB	39..151	CDD:238001	42/97 (43%)
		CUB	<200..286	CDD:238001	30/86 (35%)
		LDLa	292..326	CDD:238060	14/33 (42%)