DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq5 and COQ5

DIOPT Version :9

Sequence 1:	NP_001285193.1	Gene:	Coq5 / 32272	FlyBaseID:	FBgn0030460	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_013597.1	Gene:	COQ5 / 854930	SGDID:	S000004578	Length:	307	Species:	Saccharomyces cerevisiae

Alignment Length:	299	Identity:	131/299 - (43%)
Similarity:	184/299 - (61%)	Gaps:	15/299 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LSLARRFVHTRTASQSAQNSKGMASGAESISGKEKTTHFGFQTVRESEKEQKVHEVFEQVANSYD 74
            |.|:|.|.....|.:..:.:..::|.||  ..::|.||||.:||.:|.|::.|.:||..|||.||
Yeast    17 LRLSRCFTQAHRACKEEEVNSPLSSAAE--QPEQKYTHFGSKTVLKSTKQKLVGDVFSSVANRYD 79

  Fly    75 VMNDAMSLGIHRVWKDVFVERL------GPTHGMRLLDMAGGTGDITFRYLRYLNNQPNPQQRPS 133
            :|||.|||||||:|||.|:.:|      ..|..:..:|:|||:|||.|..|.:..::....:  |
Yeast    80 LMNDVMSLGIHRLWKDHFINKLDAGKRPNSTTPLNFIDVAGGSGDIAFGLLDHAESKFGDTE--S 142

  Fly   134 HVTVSDINQHMLNVGEERAKRLGLTTDQLSNCTVAWQCADAEKLPFPDA-SFTAYTIAFGIRNCT 197
            .:.:.|||..||..||:||...|   ....:..|.:..::.|||...|: |...||::|||||.|
Yeast   143 TMDIVDINPDMLKEGEKRAMEQG---KYFKDPRVRFLVSNGEKLEEIDSDSKDIYTVSFGIRNFT 204

  Fly   198 HVDKVLSEAYRVLQPGGRFMCLEFSHLTNETMQWLYDQYSFQVIPPMGQLLAGQWQAYQYLVESI 262
            .:.|.|:.|||||:|||.|.|||||.:.|..|.:.|.|:: :|:|.||.::|..:.:||||||||
Yeast   205 DIQKGLNTAYRVLKPGGIFYCLEFSKIENPLMDFAYQQWA-KVLPVMGSMIANDYDSYQYLVESI 268

  Fly   263 RRFPKQEQFKQMIEQAGFDQVSYENLTFGVVSIHSGFKL 301
            .|||.||.||.|||:|||....||:||||:.:||.|.|:
Yeast   269 ERFPDQETFKSMIEKAGFKSAGYESLTFGICAIHWGIKV 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq5	NP_001285193.1	ubiE	50..301	CDD:234689	117/257 (46%)
COQ5	NP_013597.1	Ubie_methyltran	67..306	CDD:395966	113/244 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344614
Domainoid	1	1.000	207	1.000	Domainoid score	I522
eggNOG	1	0.900	-	-		E1_COG2226
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6559
Inparanoid	1	1.050	228	1.000	Inparanoid score	I736
Isobase	1	0.950	-	0	Normalized mean entropy	S913
OMA	1	1.010	-	-		QHG62601
OrthoFinder	1	1.000	-	-		FOG0004442
OrthoInspector	1	1.000	-	-		oto99739
orthoMCL	1	0.900	-	-		OOG6_101003
Panther	1	1.100	-	-	LDO	PTHR43591
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R235
SonicParanoid	1	1.000	-	-		X3146
TreeFam	1	0.960	-	-
	16	15.740