DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq5 and coq-5

DIOPT Version :9

Sequence 1:	NP_001285193.1	Gene:	Coq5 / 32272	FlyBaseID:	FBgn0030460	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_498704.1	Gene:	coq-5 / 176099	WormBaseID:	WBGene00000765	Length:	285	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	140/287 - (48%)
Similarity:	189/287 - (65%)	Gaps:	25/287 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RRFVHTRTASQSAQNSKGMASGAESISGKEKTTHFGFQTVRESEKEQKVHEVFEQVANSYDVMND 78
            |:|...:..|.:.::..|            |.|||||..|.|:|||||||.||..||..||:|||
Worm    21 RQFSVNQVNSDNKRSEPG------------KKTHFGFTDVDEAEKEQKVHHVFANVAKKYDLMND 73

  Fly    79 AMSLGIHRVWKDVFVERLGPTHGMRLLDMAGGTGDITFRYLRYLNNQPNPQQRPSHVTVSDINQH 143
            |||:|:||:|||.:|..|...:..:.||||||||||.||.||:     :|..:   ||||||||.
Worm    74 AMSMGVHRLWKDYYVGGLQVPYNAKCLDMAGGTGDIAFRILRH-----SPTAK---VTVSDINQP 130

  Fly   144 MLNVGEERAKRLGLTTDQLSNCTVAWQCADAEKLPFPDASFTAYTIAFGIRNCTHVDKVLSEAYR 208
            ||:||::||::    ...:......|.||:||::||...::..:|::||||||||.:||:.||:|
Worm   131 MLDVGKKRAEK----ERDIQPSRAEWVCANAEQMPFESNTYDLFTMSFGIRNCTHPEKVVREAFR 191

  Fly   209 VLQPGGRFMCLEFSHLTNETMQWLYDQYSFQVIPPMGQLLAGQWQAYQYLVESIRRFPKQEQFKQ 273
            ||:|||:...||||.: |..::.:||.|||.|||.:|::||....:|||||||||:||.|::|.:
Worm   192 VLKPGGQLAILEFSEV-NSALKPIYDAYSFNVIPVLGEILASDRASYQYLVESIRKFPNQDEFAR 255

  Fly   274 MIEQAGFDQVSYENLTFGVVSIHSGFK 300
            :|.:.||..|.||||||||.|||.|.|
Worm   256 IIREEGFSNVRYENLTFGVCSIHKGMK 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq5	NP_001285193.1	ubiE	50..301	CDD:234689	131/251 (52%)
coq-5	NP_498704.1	MenG_MenH_UbiE	57..282	CDD:273884	122/237 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162086
Domainoid	1	1.000	253	1.000	Domainoid score	I1130
eggNOG	1	0.900	-	-		E1_COG2226
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6559
Inparanoid	1	1.050	269	1.000	Inparanoid score	I1850
Isobase	1	0.950	-	0	Normalized mean entropy	S913
OMA	1	1.010	-	-		QHG62601
OrthoDB	1	1.010	-	-		D1125002at2759
OrthoFinder	1	1.000	-	-		FOG0004442
OrthoInspector	1	1.000	-	-		oto18156
orthoMCL	1	0.900	-	-		OOG6_101003
Panther	1	1.100	-	-	LDO	PTHR43591
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R235
SonicParanoid	1	1.000	-	-		X3146
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750