Protein Alignment CG4332 and R166.2

DIOPT Version :10

• Sequence 1: NP_572861.1
• Gene: CG4332 / 32267
• FlyBaseID: FBgn0030456
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_496269.1
• Gene: R166.2 / 174620
• WormBaseID: WBGene00011302
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 490
• Identity: 161/490 - (32%)
• Similarity: 248/490 - (50%)
• Gaps: 50/490 - (10%)

  Fly    91 PLRTRRNGSLYLHVVLALEGE---PLEWRSLRRDGPTVVHTMSLTDYIVP--RAEAFKLLGDSEK 150
            |....||.||:||..:...|:   |.:....:..  .:..:..|..|...  |..:..|.|:||:
 Worm   131 PAALLRNDSLWLHTFIVKAGQSPNPKDRNYFKNQ--IIYKSYQLNKYKKKYYRKTSNLLTGESEQ 193

  Fly   151 G----AAAAVQEKEKKKASTTGRPSTHIRSNVYVTLLNDLYSVSQADVPPEMAPLIRVNRNQQIL 211
            .    |.|.:.:.|         ...|...|:.::|:.|....::..:||.::..|..|.:..|.
 Worm   194 SDEDLAKAQIMKYE---------VLNHWHPNISISLVVDQTPWARGQIPPPLSEDIEFNEDGTIY 249

  Fly   212 -PILQTDTFNTRLKDLVPVTRNTTEFTFSFHYKPVGVGKLRLML--LMEHATQALLTIGFATKD- 272
             |||..:.:.....|..|:.....:...:..|.|:.|.|.::..  .|:...|::|::..|..|
 Worm   250 KPILFYNNWWNLGADYQPINETVKDLNLTITYYPMSVFKYQMYASQRMQSQWQSMLSMDGADMDD 314

  Fly   273 --IDEVKGIFSDTNVYLLCGTIFVSSIHMLFDFLSFKNDVAFWRKKQSYEGLSSRTTMWRAFSQI 335
              .|.:|....:||..||..|:.||.:|.:|:||:||||:.||..::...|||.|:.::..|..:
 Worm   315 DGHDSMKQALLETNPILLAVTMIVSLLHTVFEFLAFKNDIQFWNNRKDLVGLSVRSVLFNIFQSL 379

  Fly   336 VIFFYLLDENTSYLVLVPVGLGTLIELWKCKKIFRLELSFS----GLVRRKLEQVDRRNGDQAGV 396
            ::|.|:.|..|:.:|.|.||:|.|||.||..|:..:.:.:.    |::.|.:            :
 Worm   380 IVFLYICDNETNTMVKVTVGIGLLIECWKIPKVMNVSIDWQNKWFGVIPRLV------------I 432

  Fly   397 KSGQLAEEQKTDQFDRQGMRYLSYLLYPLCICGAVYSLLYQPHRSWYSWTLNSLVNGVYAFGFLF 461
            .......|.:|..:|:...:||.:.|:||.:..|:||::|...:.||||.||.|...:..|||:.
 Worm   433 SDKGSYVESETKIYDQMAFKYLGWALFPLLVGYAIYSVIYVEQKGWYSWVLNMLYGFLLTFGFIT 497

  Fly   462 MLPQLFVNYKLKSVAALPWRAFMYKAFNTFIDDFFAFIITMPTAHRVACLRDDIVFIIYLYQRWL 526
            |.||||:||||||||.||||...||..||||||.|||:|.||..:|:.|.||||:|:|||||||.
 Worm   498 MTPQLFINYKLKSVAHLPWRMLTYKFINTFIDDLFAFVIRMPLLYRIGCFRDDIIFLIYLYQRWA 562

  Fly   527 YPVDKSRL-DTGLSISE-------TPDTGNSSSAS 553
            |.:|.:|| :.|.|:.:       ||....||..|
 Worm   563 YRIDPTRLNEFGTSLEKETGAPAPTPAVEGSSEPS 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4332	NP_572861.1	CLPTM1	7..436	CDD:461689	94/363 (26%)
R166.2	NP_496269.1	CLPTM1	24..472	CDD:461689	94/363 (26%)