DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4332 and CLPTM1

DIOPT Version :10

Sequence 1:NP_572861.1 Gene:CG4332 / 32267 FlyBaseID:FBgn0030456 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_001285.1 Gene:CLPTM1 / 1209 HGNCID:2087 Length:669 Species:Homo sapiens


Alignment Length:501 Identity:178/501 - (35%)
Similarity:266/501 - (53%) Gaps:55/501 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    79 DQNFEHDFEVDVPLRTRRNGSLYLHVVLALEG---EPLEWRSLRRDGPTVVHTMSLTDYIVPRAE 140
            |..:||..|:|:|...::|||:|:||.....|   :|.: ::|.|...||..:..:..|...|.:
Human   143 DGCYEHFAELDIPQSVQQNGSIYIHVYFTKSGFHPDPRQ-KALYRRLATVHMSRMINKYKRRRFQ 206

  Fly   141 AFK--LLGDSEKGAAAAVQEKEKKKASTTG--RPSTHIRSNVYVTLLNDLYSVSQADVPPEMAPL 201
            ..|  |.|::|      ...:..|:|...|  ...:|...|:.:.:::|.....:..|||.:...
Human   207 KTKNLLTGETE------ADPEMIKRAEDYGPVEVISHWHPNITINIVDDHTPWVKGSVPPPLDQY 265

  Fly   202 IRVNR-NQQILPILQTDTFNTRLKDLVPVTRNTTEFTFSFHYKPVGVGKLRLMLLMEHATQALLT 265
            ::.:. :....||:..:.:....||..|:..:.........:.|:.:.:.:|     :|.|:..:
Human   266 VKFDAVSGDYYPIIYFNDYWNLQKDYYPINESLASLPLRVSFCPLSLWRWQL-----YAAQSTKS 325

  Fly   266 ----IG-----FATKDIDEVKGIFSDTNVYLLCGTIFVSSIHMLFDFLSFKNDVAFWRKKQSYEG 321
                :|     .:.::.|.||....:||.|||..||.||.:|.:|:||:||||:.||..:||.||
Human   326 PWNFLGDELYEQSDEEQDSVKVALLETNPYLLALTIIVSIVHSVFEFLAFKNDIQFWNSRQSLEG 390

  Fly   322 LSSRTTMWRAFSQIVIFFYLLDENTSYLVLVPVGLGTLIELWKCKKIFRLELSFSGLVRRKLEQV 386
            ||.|:..:..|...|:..|:||..|:::|.|.|.:|.||:|||..|:..:.|.            
Human   391 LSVRSVFFGVFQSFVVLLYILDNETNFVVQVSVFIGVLIDLWKITKVMDVRLD------------ 443

  Fly   387 DRRNGDQAGV------KSGQLAEEQKTDQFDRQGMRYLSYLLYPLCICGAVYSLLYQPHRSWYSW 445
              |....||:      |......|..|..:|....||||::|:||..|.|||||||..|:.||||
Human   444 --REHRVAGIFPRLSFKDKSTYIESSTKVYDDMAFRYLSWILFPLLGCYAVYSLLYLEHKGWYSW 506

  Fly   446 TLNSLVNGVYAFGFLFMLPQLFVNYKLKSVAALPWRAFMYKAFNTFIDDFFAFIITMPTAHRVAC 510
            .|:.|...:..|||:.|.||||:||||||||.||||...|||.||||||.|||:|.||..:|:.|
Human   507 VLSMLYGFLLTFGFITMTPQLFINYKLKSVAHLPWRMLTYKALNTFIDDLFAFVIKMPVMYRIGC 571

  Fly   511 LRDDIVFIIYLYQRWLYPVDKSRL-DTGLSISETPDTGNSSSASIA 555
            ||||:||.|||||||:|.||.:|: :.|:| .|.|    :::|.:|
Human   572 LRDDVVFFIYLYQRWIYRVDPTRVNEFGMS-GEDP----TAAAPVA 612

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4332NP_572861.1 CLPTM1 7..436 CDD:461689 109/379 (29%)
CLPTM1NP_001285.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..50
CLPTM1 57..497 CDD:461689 109/379 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 614..669
Blue background indicates that the domain is not in the aligned region.

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