Protein Alignment HOXC10 and unpg

DIOPT Version :10

• Sequence 1: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Sequence 2: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 335
• Identity: 84/335 - (25%)
• Similarity: 127/335 - (37%)
• Gaps: 84/335 - (25%)

Human    53 LSKRDEGSSPSLALNTYPSY--------------LSQLDSWGDPKAAYRLEQPVGRPLSS----- 98
            ||.|...:|.:|.|..:|.|              |:.|.:.|    .|....|.|.|.:.
  Fly    66 LSARAMVASSALGLTQFPLYNPWLHGYFAQNHERLTHLIAGG----CYLPSSPAGHPAAQQPQAQ 126

Human    99 ------CSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASP---- 153
                  ..:||:         ::.||:........|.:..||.:.......|....||...
  Fly   127 AQPQPPPPHPPT---------HALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMN 182

Human   154 -----SYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTP---- 209
                 |.|...:..|.:.|....   |.:|  ||....|:.|......|.|  .||.|.:|
  Fly   183 QDYVHSLSVHARLQHMAAAGRMH---EDQA--NPGMAQLQEPTPPQAHSSP--AKSGSHSPMEPA 240

Human   210 --------------SPNEIKTEQSLAGPKGSPSESEKER--AKAADSSPDTSDNEAKEE------ 252
                          |.::|....|   |:....|.:|.|  |.....|.|.||:|..:.
  Fly   241 LDVGMDEDFECSGDSCSDISLTMS---PRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGG 302

Human   253 IKAENTTGNWLTAKS-GRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWF 316
            :..:::.||..::.| .|::|..:|..|.||||:||....||:...|.:|:.::.|::.||||||
  Fly   303 MGGKDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWF 367

Human   317 QNRRMKLKKM 326
            ||||.|.|::
  Fly   368 QNRRAKWKRV 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		25/110 (23%)
		Homeodomain	269..325	CDD:459649	26/55 (47%)
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	24/51 (47%)