DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4404 and AgaP_AGAP004174

DIOPT Version :9

Sequence 1:	NP_572838.2	Gene:	CG4404 / 32241	FlyBaseID:	FBgn0030432	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	XP_001688419.2	Gene:	AgaP_AGAP004174 / 5667711	VectorBaseID:	AGAP004174	Length:	326	Species:	Anopheles gambiae

Alignment Length:	273	Identity:	57/273 - (20%)
Similarity:	95/273 - (34%)	Gaps:	79/273 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RFVQFVENQPCLWNYTHPGYSKKEDVQRAWQQVANDIKDTVRNCRERWRTIRSSFLRSLKLARTQ 81
            :.:|..:..|.|::..||.|..|....:|..::.:|::..      |..|.....||.::..|||
Mosquito    12 QLIQSYKKHPVLYDMRHPRYYNKTFRGKALSEIVDDVQQV------RPDTSMKDVLRKIQTMRTQ 70

  Fly    82 TGRGKRK----------------YYLSKYLQFLVPFTKSRSCHKQLPGM---------------- 114
            .|:...|                :|.|  |.||....|.||. ..:|.|
Mosquito    71 FGQELTKTRRHSMNGSMYQPTVWWYES--LSFLQNHIKHRSV-DAVPTMENDGWKSEHDDSSSYN 132

  Fly   115 --VLRKPGQAATAQQEDEVVAAEEEAKVSDGEMPLDVQVSEEEHRRNQEQDREQPTACLPLRLHS 177
              ::|..|.:.:..:.:.|    |....:||     ::...|.|......|.:...|.....:.|
Mosquito   133 VSIVRNRGGSGSPSEINNV----EYEHSTDG-----MEYETEVHYEINSIDMKDIKALELKPIVS 188

  Fly   178 IKVEHDSSNANQQL---ERMVSQQSLVSVPAAALGNHLGWSDLTQWFKGHGSGHHKLTTTTTTPT 239
            ..|...|....:.|   :|.|::.|.||:..|.:.|                 ||       :||
Mosquito   189 ASVSAGSKRDARYLDRSDRKVARTSQVSLKDAKIVN-----------------HH-------SPT 229

  Fly   240 SPPPPPQPATSAL 252
            ..|.|.:|:|:.:
Mosquito   230 PEPVPAEPSTATV 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4404	NP_572838.2	MADF	17..103	CDD:214738	23/101 (23%)
CG4404	NP_572838.2	BESS	267..301	CDD:281011
AgaP_AGAP004174	XP_001688419.2	MADF_DNA_bdg	13..101	CDD:287510	21/95 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910