DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4404 and CG12609

DIOPT Version :9

Sequence 1:	NP_572838.2	Gene:	CG4404 / 32241	FlyBaseID:	FBgn0030432	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_728194.1	Gene:	CG12609 / 32862	FlyBaseID:	FBgn0030952	Length:	324	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	66/323 - (20%)
Similarity:	111/323 - (34%)	Gaps:	126/323 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FNVRFVQFVENQPCLWNYTHPGYSKKEDVQR-AWQQVAND---------IKDTVRNCRERWRTIR 68
            ||:|.|.....|||||..|.|.| |..|::| :|:::|:.         |:..:||.|.:....:
  Fly    31 FNLRLVDLYREQPCLWKITLPAY-KDADMKRSSWEKIASQLGSHLSAEFIRCRMRNMRYQLNVYK 94

  Fly    69 SSFLRSLKLARTQTGRGK---RKYYLSKYLQFL----------------------VP----FTKS 104
               |:.::...| :|:||   :.||:.:: .||                      :|    |.|.
  Fly    95 ---LQMIEYQMT-SGKGKPPEKPYYVDRF-AFLEQEDGAEESDNQQSNANAKKQNIPRSERFAKL 154

  Fly   105 RSCHKQLPGMVLRKPGQAA------TAQQEDEVVAAEEEAKVSD--------------------- 142
            .| ...|..|..|:...|:      :.|:..::|....:|:|..
  Fly   155 WS-DFNLKSMTKRESTDASSKESHRSGQRIADMVKMRMDAQVGPLAFDRPRLKIPDFKQNIIWKR 218

  Fly   143 --GEMPLDVQV----------------SEEEHRRNQEQ-DREQPTACLPLRLHSIKVEHDSSNAN 188
              |....|..|                |..:.:.||:. |.||||..   |:....:.:|..:.:
  Fly   219 NLGNRSSDTSVGDLSETLSTLQARPGDSVSKTKMNQKDLDSEQPTTS---RMAKYALANDGQSED 280

  Fly   189 QQLERM-----VSQQSLVSVPAAALGNHLGWSDLTQWFKGHGSGHHKL--TTTTTTPTSPPPP 244
            ::|.:|     ..|:||                        ..||.:.  ..|.:.|:.|..|
  Fly   281 EELYKMHWKVRTGQRSL------------------------RPGHDRCQKLPTLSLPSKPDEP 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4404	NP_572838.2	MADF	17..103	CDD:214738	30/124 (24%)
CG4404	NP_572838.2	BESS	267..301	CDD:281011
CG12609	NP_728194.1	MADF_DNA_bdg	35..122	CDD:287510	25/92 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000