Protein Alignment pira and Semp2l1

DIOPT Version :10

• Sequence 1: NP_572827.1
• Gene: pira / 32229
• FlyBaseID: FBgn0030420
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001157758.1
• Gene: Semp2l1 / 408191
• MGIID: 3644687
• Length: 478
• Species: Mus musculus
• Alignment Length: 509
• Identity: 104/509 - (20%)
• Similarity: 178/509 - (34%)
• Gaps: 181/509 - (35%)

  Fly   134 PPN-AMAGEEHSPAVVKPSETAVANNGCQP----------------AASATKGKKHKKSPCGSPG 181
            ||: .:|.|:.|...|:.|:....|   ||                .|.|..||.||: |..:..
Mouse    59 PPDLELAIEQFSKGQVRKSQGETPN---QPKPLELTEGPPEQVVTGRAPADSGKGHKR-PYSAME 119

  Fly   182 ENNDGQVILSADQDANTNTKAKKQKKCHIAKD-------NNGIQAASSHDNPSSSGNKQGSHNST 239
            ||.  |:             .:|:||..:.::       ...|:...|.|:..|....:....||
Mouse   120 ENE--QI-------------PQKEKKRRLLQNLKLILIKAGKIKGGESEDSHGSETTLRDPEPST 169

  Fly   240 AITSNSTMTSN----------------------GLRG--VQPAEDAPAISQWIQSRNNAAVSKKS 280
            .:.....::.:                      |.||  ::|...|..|..  .||.|:.:..|.
Mouse   170 VVALKECLSPDEREKCCFEETSVTEKKGCVKVEGRRGNSLEPGTQAQIILD--SSRGNSLLPNKM 232

  Fly   281 EETAG-------GSQSRVQSNVASISSPAVKATSDAAIPTPAERAERSRLRRNRNWILSRDVDED 338
            ...|.       ..:.|....:..|:....|...:|..|.|.|....||.:
Mouse   233 AVLAAQKKPLRDHEKHREMDQILDITEDMEKEIENALGPGPQEEILSSRFK-------------- 283

  Fly   339 AVVLVSSGDEETTAADDGQTERRLSPDENQTLFTYPPTGTGGLSITIKDFMCLSKGSYLNDIIID 403
              :|::.||.:|                                        |..|.:|||.:|:
Mouse   284 --LLITRGDIQT----------------------------------------LKNGQWLNDEVIN 306

  Fly   404 FYLRWLKNNIIPEEQRDR----THIFSTFFHKRLTTRTNPRNTKQTAAQKRHERVEKWTRNVNIF 464
            ||:     |::.|...::    .|:|||||:.:|             ....:..|::|||.:|:|
Mouse   307 FYM-----NLLVERNENQGYPALHVFSTFFYPKL-------------KHSGYSSVKRWTRGINLF 353

  Fly   465 DKDFIIIPFNEQSHWILAIICYPNLRSPVVNNNNVQTTLSDDIPIKQPLILIFDSLAVTSRHRAI 529
            :|:.|::|.:::.||.|.:                       |.:::..|..|||:..|.:....
Mouse   354 EKELILVPIHQRLHWSLVV-----------------------IDLRKQSIAYFDSIGQTGKSICE 395

  Fly   530 AILRDYLTCEHKAKYPNALAHV-FNKDNMPGHSVEVPQQQNLTDCGLYLLQYVE 582
            .|.: ||..|.|.:....|..: :.:.:|.  |.|:|.|.|.:|||::..:|.:
Mouse   396 TIFQ-YLQNESKTRRNIELDPLEWKQYSMA--SEEIPLQMNGSDCGMFTCKYAD 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pira	NP_572827.1	Peptidase_C48	396..585	CDD:420019	49/192 (26%)
Semp2l1	NP_001157758.1	Peptidase_C48	<231..473	CDD:420019	66/316 (21%)