Protein Alignment pira and Senp6

DIOPT Version :10

• Sequence 1: NP_572827.1
• Gene: pira / 32229
• FlyBaseID: FBgn0030420
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001100312.2
• Gene: Senp6 / 300860
• RGDID: 1304565
• Length: 1135
• Species: Rattus norvegicus
• Alignment Length: 1009
• Identity: 212/1009 - (21%)
• Similarity: 334/1009 - (33%)
• Gaps: 427/1009 - (42%)

  Fly     2 DRKETVSKDQAVRRIAHNDFIL--------VSRQLLINRADTDPD-KGSARMLIIYSSGKQHIVT 57
            ||||.......|.:..:|..:|        |.::...:.:..:|: |...:.       |:|..|
  Rat   154 DRKERKEYPPHVHKAENNPVMLSHGQGGDHVMKKTEDSESYVEPEVKRKVQQ-------KRHCST 211

  Fly    58 FKLPNLA-------------------------------CRVQDLFFQMDLQIDESTTIDCIENAG 91
            ::|..|:                               |:...:.|..|||.:....:...|:.|
  Rat   212 YQLSPLSPASKKCLTHFEVSEQRECCPKCGKEKENQTRCQSCGIVFHNDLQRNCRQAVTLNESTG 276

  Fly    92 GIIHLVV--SVGFPISDNIAETVAHAEEFYRKVHQSKASSADAAPPNAMA---GEEHSPAVVKPS 151
            .::...:  :.|...|.|...|   |::||       .:|.|..|.:.:.   |..|:  .::.:
  Rat   277 PLLRTSIHQNSGGQKSQNTGLT---AKKFY-------GNSVDKIPIDILLTCDGSRHN--YIQTN 329

  Fly   152 ETAVANNGCQPAASATKGKKHKKSPCGSPGENNDGQVILSADQDANTNTKAKKQKKCHIAKDNNG 216
            ...:...|..|..:..|.:|...|....|       :|||:|.|.:.:...:::.......|:
  Rat   330 GKVILPGGKIPKITNPKERKTSVSDLNDP-------IILSSDDDDDDDRTKRRESTSPQPADS-- 385

  Fly   217 IQAASSHDNPSSSGNKQGSHNSTAITSNSTMTSNGLRGVQPAEDAPAISQWIQSRNNAAVSKKS- 280
              |.||   |:.|..|          ..:.:.:|..|..|....:||.|:    .|...:.:|:
  Rat   386 --ACSS---PAPSTGK----------VEAALNANTCRAEQEPRSSPAESE----LNTVVIPRKAR 431

  Fly   281 -EETAGGSQS------RVQSN-----VASIS------------------------SPAVKA---- 305
             ::..|.|.|      :|.::     |.|:|                        .|.:.:
  Rat   432 MKDQLGNSISTPLKRRKVNTHGALIPVTSLSCQDFGSVILNCRSIRVGTLFRLLVEPVIFSLELI 496

  Fly   306 ---------------TSD-----------------AAIPTPAER--AERSRLRRNRNW------- 329
                           |||                 .|||...::  .:....:.::.|
  Rat   497 KIRLDGPDSVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSLQLQMSKEDKVWNDCKGIN 561

  Fly   330 ------------ILSRDVDEDAVVLVSS--------------------------------GDEET 350
                        |....:|..|.|:..|                                ..||:
  Rat   562 RITSLEEQYIILIFQTGLDHQADVVFESIITDIGIRNNVCNFFAKIPFEEANSRLVACTRSYEES 626

  Fly   351 TAADDGQTERRL------------------------SPDENQTLF--------TY-PPTGTGGLS 382
            ...:..|.|.::                        ...|:.|:|        .| ||...||:|
  Rat   627 IKGNCVQKENKVKTVSFESKIQLRSKQELQFFDDEEEAGESHTIFIGPVEKLIVYPPPPAKGGIS 691

  Fly   383 ITIKDFMCLSKGSYLNDIIIDFYLRWLKNNIIPEEQRDRTHIFSTFFHKRLT--TRTNPRNTKQT 445
            :|.:|..|||:|.:|||:||||||::|....:.:|..||.||||:||:|||.  .|.|...|..:
  Rat   692 VTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNSETTNLS 756

  Fly   446 AAQKRHERVEKWTRNVNIFDKDFIIIPFNEQSHWILAIICYPNLRSPVVNNN------------- 497
            ..||||.||:.|||:|:||:||||.:|.||.:||.||::|:|.|..|....|
  Rat   757 IQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKPS 821

  Fly   498 ---------------------------------------------------------NVQTTL-- 503
                                                                     :|:.::
  Rat   822 RAEDSYVSSASEVDACSQNSAAKPVIKKMLHRKHCLAVTDSSAAQEDSEPCYRRNAYSVKCSMKK 886

  Fly   504 ----------------------------------------------------------------- 503
                                                                             
  Rat   887 KNHAVHENEEPSNGESACQEISDRTESEHGLQDECLNSAHHPDALSKIRLNYGDQSAEGGKLLED 951

  Fly   504 ---------------SDD-------------------IPIKQPLILIFDSLAVTSRHRAIAILRD 534
                           |||                   ...|||.||:.|||...||...:.|||:
  Rat   952 ELIDFSEDQDDPDDSSDDGLLADENYNSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILRE 1016

  Fly   535 YLTCEHKAKYPNALAHVFNKDNMPGHSVEVPQQQNLTDCGLYLLQYVEQFFTKPINDYTLPIKEL 599
            ||..|.:.|  ......|:||.|.|.:.:||||.|.:|||:|:|||||.||..||.::.||: .|
  Rat  1017 YLEVEWEVK--KGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILNFELPM-NL 1078

  Fly   600 SNWFDLLTVTKKREDIANLIKKLMNESNQQRKIL 633
            .|||....:..|||:|.|:|.||..|.::::::|
  Rat  1079 VNWFPPPRMKTKREEIRNIILKLQEEQSKEKRLL 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pira	NP_572827.1	Peptidase_C48	396..585	CDD:420019	93/361 (26%)
Senp6	NP_001100312.2	Peptidase_C48	704..>820	CDD:420019	53/115 (46%)
		Peptidase_C48	<996..1072	CDD:420019	37/77 (48%)