DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12717 and Senp1

DIOPT Version :9

Sequence 1:	NP_001285167.1	Gene:	CG12717 / 32229	FlyBaseID:	FBgn0030420	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_038936284.1	Gene:	Senp1 / 300193	RGDID:	1310275	Length:	724	Species:	Rattus norvegicus

Alignment Length:	541	Identity:	116/541 - (21%)
Similarity:	207/541 - (38%)	Gaps:	141/541 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 ETVAHAE-EFYRKVHQSKASSADAAPPNAMAGEEHSPAVVKP--------SETAVANNGCQPAAS 165
            |||...| |.||::.|            .:.|::.|  |.||        |....:|......:.
  Rat   242 ETVQEEEKEIYRQLLQ------------MVTGKQFS--VAKPTTHFPLHLSRCLSSNKNSLKDSL 292

  Fly   166 ATKGKKHKKSPCGSPGENNDGQVILSADQDANTNTKAKKQKKCHIA---KD---NNGIQAASSHD 224
            ...|........||...::....||:|.:..:.:..:.......:|   ||   ::.:.|....|
  Rat   293 LRNGNSCASHVIGSDTSSSGSASILTAQEQLSHSAHSLISGTPDVAFGSKDSALHHHLSAPHQPD 357

  Fly   225 N-PSSSGNKQGSHNSTAITSNSTMTSNGLRGVQPAE------------------DAPAISQ---W 267
            : |:|:...:||.:...:....:.|. ..|.:.|.:                  .:|...|   |
  Rat   358 SLPASNPQSEGSDSVILLKVKESQTP-ASRYLSPLKRSTCPYIIPYSAVTDLLSSSPTFFQAELW 421

  Fly   268 IQ-------SRNNAAVSKKSEETAGGSQSRVQSNVASISSPAVKATSDAAIPTPAER------AE 319
            |:       ||....:.:..|:.|...|  :|:........||..:.:..:..|.|:      |:
  Rat   422 IKELTSVYDSRARERLRQIEEQKALALQ--LQNQRLQEQEHAVLDSVELHLRVPLEKEVPVTAAQ 484

  Fly   320 RSRLRRNRNWILSRDVDEDAVVLVSSGDEETTAADDGQTERRLSPDENQTLFTYPPTGTGGLSIT 384
            .:|.:.::   |:...||...:......|......:|..:..||.             ...|:||
  Rat   485 ETRKKSHQ---LTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSE-------------AFRLTIT 533

  Fly   385 IKDFMCLSKGSYLNDIIIDFYLRWLKNNIIPEEQRDR----THIFSTFFHKRLTTRTNPRNTKQT 445
            .||...|:..::|||.||:||:     |::.|..:::    .|.|:|||.           ||..
  Rat   534 RKDIQTLNHLNWLNDEIINFYM-----NMLMERSKEKGFPSVHAFNTFFF-----------TKLK 582

  Fly   446 AAQKRHERVEKWTRNVNIFDKDFIIIPFNEQSHWILAIICYPNLRSPVVNNNNVQTTLSDDIPIK 510
            ||  .::.|::||:.|::|..|.:::|.:...||.||::.:                       :
  Rat   583 AA--GYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDF-----------------------R 622

  Fly   511 QPLILIFDSLAVTSRHRAIAILRDYLTCE----HKAKYPNALAHVFNKDNMPGHSVEVPQQQNLT 571
            :..:..:||:...: :.|..||..||..|    .:.::......:|:|     .|.|:|||.|.:
  Rat   623 KKSVTYYDSMGGVN-NEACRILLQYLKQESVDKKRKEFDTNGWQLFSK-----KSQEIPQQMNGS 681

  Fly   572 DCGLYLLQYVEQFFTK--PIN 590
            |||::..:|.: ..||  |||
  Rat   682 DCGMFACKYAD-CITKDRPIN 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12717	NP_001285167.1	BASP1	122..319	CDD:283191	40/245 (16%)
CG12717	NP_001285167.1	Peptidase_C48	396..585	CDD:304959	49/196 (25%)
Senp1	XP_038936284.1	mukB	<433..>527	CDD:235316	17/111 (15%)
Senp1	XP_038936284.1	Peptidase_C48	<500..722	CDD:420019	64/263 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810