Protein Alignment: CG12717 and SENP6

• Sequence 1: NP_001285167.1
• Gene: CG12717
• FlyBaseID: FBgn0030420
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_056386.2
• Gene: SENP6
• HGNCID: 20944
• Length: 1112
• Species: Homo sapiens
• Alignment Length: 967
• Identity: 208/968 (21%)
• Similarity: 328/968 (34%)
• Gaps: 370/968 (38%)

  Fly     1 MDRKETVSKDQAVRRIAHNDFILVSRQLLINR---------ADTDPD-KGSARMLIIYSSGKQHI 55
            :||||.......|:::..|. :.:||...:.|         :..:|: |...:.       |:|.
Human   155 LDRKERKEYPPHVQKVEINP-VRLSRLQGVERIMKKTEESESQVEPEIKRKVQQ-------KRHC 211

  Fly    56 VTFK-LPNLACRVQDLFFQM-DLQIDESTTIDCIENAGGIIHLVV--SVGFPISDNIAETVAHAE 116
            .|:: .|.|:...:.....: |||.:....|...|:.|.::...:  :.|...|.|...|   .:
Human   212 STYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLT---TK 273

  Fly   117 EFYRKVHQSKASSADAAPPNAMAGEEHSPAVVKPSETAVANNG--CQPAASATK--GKKHKKSPC 177
            :||       .::.:..|.:.:...:.|      ..|.:..||  ..|.|...|  ..|.:|:
Human   274 KFY-------GNNVEKVPIDIIVNCDDS------KHTYLQTNGKVILPGAKIPKITNLKERKT-- 323

  Fly   178 GSPGENNDGQVILSADQDANTNTKAKK-------QKKCHIAKDNNGIQAASSHDN---------- 225
             |..:.||..::.|.|.|.|..|..::       ...|.....:.|...|:.::|
Human   324 -SLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRS 387

  Fly   226 -PSSS-----------------GNK------------------------QGSHNSTAITSNSTMT 248
             |..|                 ||.                        |.|.:|..:...|...
Human   388 IPEDSELNTVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRV 452

  Fly   249 SNGLRGV----------------QPAEDAPAI---------SQWIQSRN---------NAAVSKK 279
            ....|.:                :|..|...|         .:|...|.         .|...|.
Human   453 GTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKL 517

  Fly   280 SEETAGGSQSRVQSNVASISSPAVKATS----------DAAIPTPAERAERS-----RLRRNRNW 329
            |.:.....:.:|.::...::    |.|:          ...:..||.....|     .::.|.:.
Human   518 SIQLQMNKEDKVWNDCKGVN----KLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISN 578

  Fly   330 ILSRDVDEDA---VVLVSSGDEETTAADDGQTERRL------------------------SPDEN 367
            ..::...|:|   :|..:...||:.....||.|.::                        ...||
Human   579 FFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGEN 643

  Fly   368 QTLF--------TY-PPTGTGGLSITIKDFMCLSKGSYLNDIIIDFYLRWLKNNIIPEEQRDRTH 423
            .|:|        .| ||...||:|:|.:|..||::|.:|||:||||||::|....:.:|..||.|
Human   644 HTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIH 708

  Fly   424 IFSTFFHKRLT--TRTNPRNTKQTAAQKRHERVEKWTRNVNIFDKDFIIIPFNEQSHWILAIICY 486
            |||:||:|||.  .|.|...|..:..||||.||:.|||:|:||:||||.:|.||.:||.||::|:
Human   709 IFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCF 773

  Fly   487 PNLRSP--------------------------------------------------------VVN 495
            |.|..|                                                        |::
Human   774 PGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVID 838

  Fly   496 NN--------------------------------------------------------------- 497
            :|
Human   839 SNPGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTH 903

  Fly   498 ------NVQTTLSDDIP-----------------------------------------------I 509
                  .::...||:.|                                               .
Human   904 HTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQWHLKPTIC 968

  Fly   510 KQPLILIFDSLAVTSRHRAIAILRDYLTCEHKAKYPNALAHVFNKDNMPGHSVEVPQQQNLTDCG 574
            |||.||:.|||...||...:.|||:||..|.:.|  ......|:||.|.|.:.:||||.|.:|||
Human   969 KQPCILLMDSLRGPSRSNVVKILREYLEVEWEVK--KGSKRSFSKDVMKGSNPKVPQQNNFSDCG 1031

  Fly   575 LYLLQYVEQFFTKPINDYTLPIKELSNWFDLLTVTKKREDIANLIKKLMNESNQQRK 631
            :|:|||||.||..||..:.||: .|:|||....:..|||:|.|:|.||..:.:::::
Human  1032 VYVLQYVESFFENPILSFELPM-NLANWFPPPRMRTKREEIRNIILKLQEDQSKEKR 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12717	NP_001285167.1	BASP1	122..319	CDD:283191	44/304 (14%)
		Peptidase_C48	396..585	CDD:304959	94/363 (26%)
SENP6	NP_056386.2	Protease	666..1112		117/426 (27%)
		Peptidase_C48	680..>825	CDD:304959	52/145 (36%)
		Peptidase_C48	<973..1049	CDD:304959	37/78 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C107338981
eggNOG	1	0.900				E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000927
OrthoInspector	1	1.000				T610033
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR46896
Phylome	1	0.910		0.889	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1602
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	8	7.830