DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12717 and ulp2

DIOPT Version :9

Sequence 1:	NP_001285167.1	Gene:	CG12717 / 32229	FlyBaseID:	FBgn0030420	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_593475.2	Gene:	ulp2 / 2542268	PomBaseID:	SPAC17A5.07c	Length:	638	Species:	Schizosaccharomyces pombe

Alignment Length:	487	Identity:	134/487 - (27%)
Similarity:	210/487 - (43%)	Gaps:	91/487 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 HIAKDNNGIQAASSHDNPSSSGNKQGSHNSTAITSNSTMTSNGLRGVQPAEDAPAISQWIQSRNN 273
            |:.....|:......|...:|.:.............||        :.|......:...::..::
pombe   195 HVESARAGLDLLDQSDFSLTSPSSAKEFKQLLTLKQST--------IIPRTPQKTVRSIVKQTSS 251

  Fly   274 AAVSKKSEETAGGSQSRVQSNVASISSPAVKATSDAAIPTPAERAERSRLRRNRNWILSRDVDED 338
            ...||..:.:...|.:...||........:|.::.::...|.  |......:|::...:.:...|
pombe   252 PHSSKMPKHSLPSSPTPFNSNSGDSLLSRIKNSNQSSSERPT--ANNGAQEQNQSSSSAGNTSND 314

  Fly   339 AVVLVSSGDEETTAADDGQTERRLSPDENQTLFTYPPTGTGGLSITIKDFMCLSKGSYLNDIIID 403
            ...|.|.|.::|..:|...|          |:..||.:||..::||..|...|::|.:|||.|:|
pombe   315 FSTLCSQGSDKTLLSDASCT----------TILVYPFSGTNSIAITNTDLTRLNEGEFLNDTIVD 369

  Fly   404 FYLRWL------KNNIIPEEQRDRTHIFSTFFHKRLTTRTNPRNTKQTAAQKRHERVEKWTRNVN 462
            ||||:|      :|   |....| ||||:|||:.|||::  .::.|:..    |..|.|||:.|:
pombe   370 FYLRYLYCKLQTQN---PSLAND-THIFNTFFYNRLTSK--DKDGKRLG----HRGVRKWTQKVD 424

  Fly   463 IFDKDFIIIPFNEQSHWILAIICYPNLRSPV--------------VNNNNVQTTLSDDIPIKQPL 513
            :|.|.:||:|.||..||.|||||..:...||              |...:...|...::....|.
pombe   425 LFHKKYIIVPINETFHWYLAIICNIDRLMPVDTKLEEQDEIVMSSVEQPSASKTRQAELTSNSPA 489

  Fly   514 ILIFDSLAVTSRHR-AIAILRDYLTCEHKAKYPNALAHVFNKDN-------MPGHSVEVPQQQNL 570
            ||||||||  :.|: |:..||:||           |...|.:.|       :.|...:||||.|.
pombe   490 ILIFDSLA--NLHKGALNYLREYL-----------LEEAFERKNVHLKSTDIRGFHAKVPQQSNF 541

  Fly   571 TDCGLYLLQYVEQFFTKPIN------DYTLPIKELSNW---FDLLTVTKKREDIANLIKKLMNE- 625
            :|||:|.|.:||.|...|..      |.:|...:..|:   ::|..:...|.|:..||::|..|
pombe   542 SDCGIYALHFVELFLETPEQVIANTLDKSLRRTDAKNFDQQWNLQKINTMRCDLKGLIRRLSTEW 606

  Fly   626 -SNQQRKILPVIKFPTLNGQLVMDEEDSEEEN 656
             ||.:|:.|.       :|.  .||||.|.::
pombe   607 SSNNERQSLS-------SGS--NDEEDKENDD 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12717	NP_001285167.1	BASP1	122..319	CDD:283191	14/109 (13%)
CG12717	NP_001285167.1	Peptidase_C48	396..585	CDD:304959	79/216 (37%)
ulp2	NP_593475.2	ULP1	25..592	CDD:227489	118/439 (27%)
		EB1_binding	<230..312	CDD:283565	12/91 (13%)
		Peptidase_C48	361..595	CDD:280975	86/256 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1230
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1292
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000929
OrthoInspector	1	1.000	-	-		otm47183
orthoMCL	1	0.900	-	-		OOG6_102905
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1602
SonicParanoid	1	1.000	-	-		X756
TreeFam	0	0.000	Not matched by this tool.
	9	8.790