Protein Alignment pira and Semp2l2b

DIOPT Version :10

• Sequence 1: NP_572827.1
• Gene: pira / 32229
• FlyBaseID: FBgn0030420
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_444494.1
• Gene: Semp2l2b / 114671
• MGIID: 2149738
• Length: 495
• Species: Mus musculus
• Alignment Length: 513
• Identity: 108/513 - (21%)
• Similarity: 175/513 - (34%)
• Gaps: 171/513 - (33%)

  Fly   123 HQSKASSADAAPPNAMAGEEHSPAVVKPSETAVANNGCQPAASATKGKKHKKSPCG-------SP 180
            |.||   .....|.....::..|..:..........|.:||..   ||.||: |..       ||
Mouse    69 HPSK---GQVRKPQGKTPKQLEPLELTEGSPEQVVTGRKPADG---GKGHKR-PYSVMEENEQSP 126

  Fly   181 GENNDGQVI--LSADQDAN----------TNT-KAKKQKKCHIAKDNNGIQAASSHDNPSS---- 228
            .:...|:::  |..|||.:          ||| |.|..:    ::|:.|.:...|...||:
Mouse   127 QKEKYGRLLQHLQCDQDVSSDPHRPHPFLTNTWKIKGGE----SEDSRGSERTQSDREPSTVVAL 187

  Fly   229 -------SGNKQGSHNSTAITSNSTMTSNGLRGVQPAEDAPAISQWI---QSRNNA--------- 274
                   ...|..|...........:...|.||.....|.|.....|   ..:.|:
Mouse   188 KECLSPEEREKCCSEEKCVTEKKDCIKGEGRRGNSLEPDLPGTQAQIILDSGKGNSLFPNKVAVL 252

  Fly   275 AVSKKSEETAGGSQSRVQSNVASISSPAVKATSDAAIPTPAERAERSRLRRNRNWILSRDVDEDA 339
            |..||.....|  :.|....:..|:....|...:|..|.|.|....||.:
Mouse   253 AAEKKPITDRG--KGREMDQILDITEDMEKEIENALGPGPQEEILSSRFK--------------- 300

  Fly   340 VVLVSSGDEETTAADDGQTERRLSPDENQTLFTYPPTGTGGLSITIKDFMCLSKGSYLNDIIIDF 404
             :.:|.||.:|                                        |..|.:|||.:|:|
Mouse   301 -LQISRGDIQT----------------------------------------LENGQWLNDEVINF 324

  Fly   405 YLRWLKNNIIPEEQRDR----THIFSTFFHKRLTTRTNPRNTKQTAAQKRH---ERVEKWTRNVN 462
            |:     |::.|...::    .|:|||||:.:|                :|   ..|::|||.:|
Mouse   325 YM-----NLLVERNENQGYPALHVFSTFFYPKL----------------KHGGYSSVKRWTRGIN 368

  Fly   463 IFDKDFIIIPFNEQSHWILAIICYPNLRSPVVNNNNVQTTLSDDIPIKQPLILIFDSLAVTSRHR 527
            :|:|:.|::|.:::.||.|.:                       |.:::..|:..||:..|.:..
Mouse   369 LFEKELILVPIHQRVHWSLVV-----------------------IDLRKRSIVYLDSMGQTGKSI 410

  Fly   528 AIAILRDYLTCEHKAKYPNALAHVFNKDNMPGHSV---EVPQQQNLTDCGLYLLQYVE 582
            ...|.: ||..|.|.:....|..:..|.    :||   |:|.|.|.:|||::..:|.:
Mouse   411 CETIFQ-YLQNESKTRRNVELDPLEWKQ----YSVTSEEIPLQLNGSDCGMFTCKYAD 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pira	NP_572827.1	Peptidase_C48	396..585	CDD:420019	50/197 (25%)
Semp2l2b	NP_444494.1	Peptidase_C48	<272..490	CDD:420019	64/297 (22%)