DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2540 and CHAC1

DIOPT Version :9

Sequence 1:	NP_572818.1	Gene:	CG2540 / 32216	FlyBaseID:	FBgn0030411	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_024305813.1	Gene:	CHAC1 / 79094	HGNCID:	28680	Length:	264	Species:	Homo sapiens

Alignment Length:	202	Identity:	85/202 - (42%)
Similarity:	110/202 - (54%)	Gaps:	15/202 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 DTENSNQLEPPAA----TDAD---VWIFGYGSLVWKTDFPYIDRRRGFVWGFKRRFYQHSIDHRG 114
            :|..::|...|:|    .|.|   :||||||||||:.||.|.|.|.|||.|:.|||:|....|||
Human    51 NTPPTSQSPTPSAQFPRNDGDPQALWIFGYGSLVWRPDFAYSDSRVGFVRGYSRRFWQGDTFHRG 115

  Fly   115 IPERPGRVVTLLPGDPAQDRVYGVAYRIAASQKGAVLDHLDYREK--NGYERCSLEFHEYPTDGA 177
            ..:.||||||||  :..:...:||||::...|....|.:|:.||.  .||:...:.|  ||.|..
Human   116 SDKMPGRVVTLL--EDHEGCTWGVAYQVQGEQVSKALKYLNVREAVLGGYDTKEVTF--YPQDAP 176

  Fly   178 -EPIQVIMYVATQANDSYAGDVWQVPCIARQIFSSAGPSGPNREYLFNLAAAMDQLFPGAVDEHL 241
             :|::.:.||||..|..|.|...: ..||.||.:..|.||.|.|||..||..|....|.|.||||
Human   177 DQPLKALAYVATPQNPGYLGPAPE-EAIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHL 240

  Fly   242 EELVACV 248
            ..:|..|
Human   241 AAIVDAV 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2540	NP_572818.1	ChaC	74..251	CDD:282590	79/178 (44%)
CHAC1	XP_024305813.1	ChaC	75..249	CDD:282590	79/178 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1238273at2759
OrthoFinder	1	1.000	-	-		FOG0001482
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101165
Panther	1	1.100	-	-	O	PTHR12192
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R197
SonicParanoid	1	1.000	-	-		X941
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.950