Protein Alignment Aven and AVEN

DIOPT Version :10

• Sequence 1: NP_572817.1
• Gene: Aven / 32215
• FlyBaseID: FBgn0030410
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_065104.1
• Gene: AVEN / 57099
• HGNCID: 13509
• Length: 362
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 73/342 - (21%)
• Similarity: 106/342 - (30%)
• Gaps: 120/342 - (35%)

  Fly    28 RSTTSSGSPPPTSRRSMVDVADSSDEPRLARRGNWQSSGAGRSSLAPQRNRDMLDTLPSDTD--- 89
            |.....|..|..|||          ||     |.|   |||.|  ||..:....:|...:.|
Human    63 RGGRGGGGAPRGSRR----------EP-----GGW---GAGAS--APVEDDSDAETYGEENDEQG 107

  Fly    90 ---------------DVEQLGLDGAPIDENARAQLRAGDFQQLAQFPSLGGGHFTFGSEREWANV 139
                           |:|:      .::..:....|..||..|..........|.|..|:||.:.
Human   108 NYSKRKIVSNWDRYQDIEK------EVNNESGESQRGTDFSVLLSSAGDSFSQFRFAEEKEWDSE 166

  Fly   140 AEGQTKLHTKAASAYFTLNLTRLNVGLQTIPLYKRMDYPASLFT-RAQIAAQEKAAERAEAVYQQ 203
            |.     ..|..||:: ::...|...||.:||..|::..|.|.. ...:...:...:|.:
Human   167 AS-----CPKQNSAFY-VDSELLVRALQELPLCLRLNVAAELVQGTVPLEVPQVKPKRTD----- 220

  Fly   204 CILKDANG---------GAKSRAP--------------SAKSNKDVAPAA-AEKPIAASAAEPDE 244
                |..|         |...|.|              ..|.|....|:. ::||.:...:..|.
Human   221 ----DGKGLGMQLKGPLGPGGRGPIFELKSVAAGCPVLLGKDNPSPGPSRDSQKPTSPLQSAGDH 281

  Fly   245 LDE---LLAMTDTQLDIGSGTI---------------------TMPMPMV------QPATPSSAA 279
            |:|   ||...|..:..|...:                     ....|.|      :|..||:
Human   282 LEEELDLLLNLDAPIKEGDNILPDQTSQDLKSKEDGEVVQEEEVCAKPSVTEEKNMEPEQPST-- 344

  Fly   280 SKNGVEE----WLDSVL 292
            |||..||    ||||::
Human   345 SKNVTEEELEDWLDSMI 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aven	NP_572817.1	None
AVEN	NP_065104.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..111		18/67 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..237		4/31 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..362		26/111 (23%)