DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11085 and LBX2

DIOPT Version :10

Sequence 1:NP_572815.3 Gene:CG11085 / 32213 FlyBaseID:FBgn0030408 Length:295 Species:Drosophila melanogaster
Sequence 2:NP_001269359.1 Gene:LBX2 / 85474 HGNCID:15525 Length:198 Species:Homo sapiens


Alignment Length:150 Identity:50/150 - (33%)
Similarity:67/150 - (44%) Gaps:30/150 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 GLLAAAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKF 179
            ||.|.|...:.| |......|||                 ..|||.|:.|||||..|:..|||:|
Human    58 GLDARALQPSEG-RAGPDALGPG-----------------PFGRKRRKSRTAFTAQQVLELERRF 104

  Fly   180 RCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEK--------DF 236
            ..||||:.::|..:|..|.|:..||.||:||||.|.||.    :|::|......:        ..
Human   105 VFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRD----VEEMRADVASLRALSPEVLCSL 165

  Fly   237 VVQDGGGAGGLGCCPSGLSS 256
            .:.:|....||...|:|..|
Human   166 ALPEGAPDPGLCLGPAGPDS 185

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11085NP_572815.3 Homeodomain 161..217 CDD:459649 28/55 (51%)
LBX2NP_001269359.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..46
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..89 10/43 (23%)
Homeodomain 86..142 CDD:459649 28/55 (51%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 173..198 4/12 (33%)
Blue background indicates that the domain is not in the aligned region.

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