DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and LBX2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001269359.1	Gene:	LBX2 / 85474	HGNCID:	15525	Length:	198	Species:	Homo sapiens

Alignment Length:	150	Identity:	50/150 - (33%)
Similarity:	67/150 - (44%)	Gaps:	30/150 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 GLLAAAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKF 179
            ||.|.|...:.| |......|||                 ..|||.|:.|||||..|:..|||:|
Human    58 GLDARALQPSEG-RAGPDALGPG-----------------PFGRKRRKSRTAFTAQQVLELERRF 104

  Fly   180 RCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEK--------DF 236
            ..||||:.::|..:|..|.|:..||.||:||||.|.||.    :|::|......:        ..
Human   105 VFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRD----VEEMRADVASLRALSPEVLCSL 165

  Fly   237 VVQDGGGAGGLGCCPSGLSS 256
            .:.:|....||...|:|..|
Human   166 ALPEGAPDPGLCLGPAGPDS 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	27/52 (52%)
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..46
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..89		10/43 (23%)
		Homeobox	88..141	CDD:278475	27/52 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..198		4/12 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810