Protein Alignment CG11085 and lbx2

DIOPT Version :10

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001007135.1
• Gene: lbx2 / 64276
• ZFINID: ZDB-GENE-001206-2
• Length: 257
• Species: Danio rerio
• Alignment Length: 195
• Identity: 58/195 - (29%)
• Similarity: 85/195 - (43%)
• Gaps: 46/195 - (23%)

  Fly    95 GGGGVASGLSAAAA--------AAGVAAGLLAAAASGANGDRDANGGSGPGSGGGTSGGYAEHKL 151
            |.....:|:||.::        |:....||..:....|.|....|               |..:.
Zfish    71 GSSASRNGISAPSSPLCALEELASKTFKGLEVSVIQAAEGREHIN---------------AFGQR 120

  Fly   152 QLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWK 216
            |.||   |.|:.|||||:.|:..||::|..|||||.|||..:|:.|.|:..||.||:||||.|.|
Zfish   121 QASK---KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLK 182

  Fly   217 RQ-----------NQLRLEQLRHQATMEKDFVVQDGGGAGGLGCCPSGLSSSFSAAAAAAAAASN 270
            |.           .::..:.|:...:||.   ::|..|..|      .:|.|.|..|...:.:|:
Zfish   183 RDLEEMKADVESLKKIPPQALQKLVSMED---MEDAHGGSG------PISPSLSPRAFPQSPSSS 238

  Fly   271  270
            Zfish   239  238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	30/55 (55%)
lbx2	NP_001007135.1	Required for convergent extension movement and hypaxial myogenesis during gastrulation. Required for the formation of thick and thin myofilaments. Required for myod1 expression in the pectoral fin bud. Required for continuous expression of cxcl12a in the posterior lateral mesoderm at the tail bud stage and in adaxial cells at the 10-somite stage. /evidence=ECO:0000269|PubMed:19216761, ECO:0000269|PubMed:22216300, ECO:0000269|PubMed:22406073	1..46
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Homeodomain	127..183	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..257		10/42 (24%)