Protein Alignment CG11085 and NKX1-2

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001139812.1
• Gene: NKX1-2 / 390010
• HGNCID: 31652
• Length: 310
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 96/288 - (33%)
• Similarity: 127/288 - (44%)
• Gaps: 64/288 - (22%)

  Fly    20 RQTDSELELSNDDSDID-IEDRSTPDSTAAGCQQELLLSHHHRRFTHHDESSVESCLSATRGPGS 83
            |::.:|:|...|.|..| :....|||:...|..|...|        ...|:..|......|.|..
Human    47 RKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPL--------EGSEAEEEEDAEDPRRPRL 103

  Fly    84 GTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGDRDANGGSGP-GSGGGTSGGYA 147
            ..                  .||....|:|....|.|.:.|:|:...:||.|| .|..|:.|...
Human   104 RE------------------RAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPR 150

  Fly   148 EHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRR 212
            ..:.:|..:..||||.|||||:.||..||.|||..:||||.:|.::|.:|:|:|||||.|:||||
Human   151 PRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRR 215

  Fly   213 TKWKRQNQLRLEQLRHQATMEKDFVVQDGGGA-----------GGLGCCPS--GLSS-------S 257
            ||||:||.            ..|...|.||||           ||.|..|.  |..:       |
Human   216 TKWKKQNP------------GADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPS 268

  Fly   258 FSAA-AAAAAAASNPCNFLTSAAAAAIF 284
            :||| ....:|||.|   ||:||..:.|
Human   269 YSAANVLFPSAASFP---LTAAAPGSPF 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	32/52 (62%)
NKX1-2	NP_001139812.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..165		34/143 (24%)
		Homeobox	167..219	CDD:278475	32/51 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..260		16/54 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4961
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.860