Protein Alignment CG11085 and HOXC13

DIOPT Version :10

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_059106.2
• Gene: HOXC13 / 3229
• HGNCID: 5125
• Length: 330
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 62/309 - (20%)
• Similarity: 87/309 - (28%)
• Gaps: 167/309 - (54%)

  Fly    66 HDESSVESCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAA----------------------- 107
            :::|:.|          ||.|.||||||||.||...|.|.|:
Human    19 YEDSAAE----------SGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLL 73

  Fly   108 ---------AAAGVAAGLL-------------------AAAASGANGDRDANGGS---------- 134
                     |..|...|.:                   ..::|...|.....|||
Human    74 PHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSHNV 138

  Fly   135 ---------GPG------SGG------------------------------------GTSG---- 144
                     .||      ||.                                    |.||
Human   139 NLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEP 203

  Fly   145 ---------GYA--------EHKLQLSK------------------------SGRKPRRRRTAFT 168
                     ||.        :.::..||                        |.|:.|::|..:|
Human   204 RHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYT 268

  Fly   169 HAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKR 217
            ..||..||:::...|:::...|..::.|.||||.||..|:||||.|.|:
Human   269 KVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	22/55 (40%)
HOXC13	NP_059106.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..50		12/19 (63%)
		HoxA13_N	54..168	CDD:463521	12/113 (11%)
		Homeodomain	261..312	CDD:459649	19/50 (38%)