DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and HOXC10

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_059105.2	Gene:	HOXC10 / 3226	HGNCID:	5122	Length:	342	Species:	Homo sapiens

Alignment Length:	116	Identity:	36/116 - (31%)
Similarity:	60/116 - (51%)	Gaps:	15/116 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 AAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQ---------LSKSGRKPRRRRTAFTHAQLAY 174
            |...|:..:.:........|...||...|:.:::         .:|||||   :|..:|..|...
Human   221 AGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRK---KRCPYTKHQTLE 282

  Fly   175 LERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWK---RQNQLR 222
            ||::|....||:...|.::::|:||::.|||.|:||||.|.|   |:|::|
Human   283 LEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIR 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	21/52 (40%)
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..271		11/52 (21%)
		Homeobox	271..324	CDD:306543	21/52 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910