Protein Alignment CG11085 and Nkx1-2

DIOPT Version :10

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001163947.1
• Gene: Nkx1-2 / 293568
• RGDID: 1306744
• Length: 305
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 89/317 - (28%)
• Similarity: 121/317 - (38%)
• Gaps: 85/317 - (26%)

  Fly     6 SFLIRDLLGD--------------LINRRQTDSELELSNDD-SDIDIEDRSTPDSTAAGCQQELL 55
            ||.:.|:|..              .:..:::..|:|...|. |...|..:.|||:...|......
  Rat    19 SFSVLDILDPQKFTRAALPPVRLAALEAKKSLVEVEAGEDACSGNPIGSQETPDAVGGGTDPASP 83

  Fly    56 LSHHHRRFTHHDESSVESCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAA 120
            :.....    .:|...|....|.| |....|:..|           .|.|.|.|.|.
  Rat    84 VEGSEA----EEEEEAEDAGRAQR-PERWQGAHAG-----------SLEAGAVAVGT-------- 124

  Fly   121 ASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYL 185
                    :.:|..|..:..|:.|.....:.:...|..||||.|||||:.||..||.|||..:||
  Rat   125 --------EESGADGLPASPGSPGSPRPRRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYL 181

  Fly   186 SVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGG-------- 242
            ||.:|.::|.:|:|:|||||.|:||||||||:||.            ..|..||.||
  Rat   182 SVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNP------------GADGAVQAGGSAPQPGTP 234

  Fly   243 ----GAGGL-----------GCCPSGLSSSFSAAAAAAAAASNPCNFLTSAAAAAIF 284
                |.||.           |..|.....::.|......|||.|   ||:.|..:.|
  Rat   235 NAVTGGGGSATGSSPGPPVPGALPFQTFPTYPATNVLFPAASFP---LTTTATGSPF 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	35/55 (64%)
Nkx1-2	NP_001163947.1	Homeodomain	157..213	CDD:459649	35/55 (64%)