Protein Alignment CG11085 and Tlx2

DIOPT Version :10

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_033418.1
• Gene: Tlx2 / 21909
• MGIID: 1350935
• Length: 284
• Species: Mus musculus
• Alignment Length: 236
• Identity: 73/236 - (30%)
• Similarity: 102/236 - (43%)
• Gaps: 72/236 - (30%)

  Fly    54 LLLSHHHRRFTHHDESS--VESCLSATRGPGSGTGSG-GGGGGGGGGGVASGLSAAAAAAGVAAG 115
            :|.:||   ..||:..|  ::..||....||.|.|.| .|...|.....:||...|:..|  .||
Mouse     5 VLAAHH---LPHHEPISFGIDQILSGPEPPGGGLGPGQSGQSHGESAAFSSGFHGASGYA--PAG 64

  Fly   116 LLAAAASGANGDRDANGGSGPG--------------------------SGGGTSGGYAEHKLQLS 154
            .||:...|:        |.|||                          ||.|.:||.|.......
Mouse    65 SLASLPRGS--------GVGPGGVIRVPAHRPLPVPPPSGAAPAVPGPSGLGGAGGLAGLTFPWM 121

  Fly   155 KSGRK----------------------------PRRR--RTAFTHAQLAYLERKFRCQKYLSVAD 189
            .|||:                            |:|:  ||:|:.:|:..|||:|..||||:.|:
Mouse   122 DSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAE 186

  Fly   190 RSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQA 230
            |:.:|:.|.:::.|||||:|||||||:||.....|..||:|
Mouse   187 RAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRA 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	29/57 (51%)
Tlx2	NP_033418.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..52		9/31 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..104		1/25 (4%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..166		5/25 (20%)
		Homeodomain	158..214	CDD:459649	28/55 (51%)