DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11085 and Barhl2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001005477.1	Gene:	Barhl2 / 104382	MGIID:	1859314	Length:	384	Species:	Mus musculus

Alignment Length:	300	Identity:	87/300 - (28%)
Similarity:	106/300 - (35%)	Gaps:	113/300 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSKSFLIRDLLGDLINRRQTDSELELSNDDSDIDIEDRSTPDSTAAGCQQELLLSHH-------- 59
            |:.||||:|:|||                         |.|.:..|.....:...||
Mouse   135 STSSFLIKDILGD-------------------------SKPLAACAPYSTSVSSPHHTPKQESNA 174

  Fly    60 -HRRFTHH-DESSVESCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAAS 122
             |..|... ::...::.|.....|.|.....|                                :
Mouse   175 AHESFRPKLEQEDGKTKLDKREDPQSDIKCHG--------------------------------T 207

  Fly   123 GANGDRDANGG--SGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYL 185
            ...|||:....  |.|                  ...:|||:.||||:..||..|||.|..||||
Mouse   208 KEEGDREITSSRESPP------------------VRAKKPRKARTAFSDHQLNQLERSFERQKYL 254

  Fly   186 SVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGGGAGGLGCC 250
            ||.||.|:|..|||::|||||||||||||||||..:.||.|..               ||.....
Mouse   255 SVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAE---------------AGNYSAL 304

  Fly   251 -----------PSGLSSSFSAAAAAAAAASNPCNFLTSAA 279
                       ||.|.|..|..|||||||.....:.|..|
Mouse   305 QRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPA 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	36/52 (69%)
Barhl2	NP_001005477.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	154..235		18/130 (14%)
		Homeobox	233..285	CDD:278475	36/51 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..384
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1387
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.770