DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1463 and ZNHIT6

DIOPT Version :9

Sequence 1:	NP_001259489.1	Gene:	CG1463 / 32211	FlyBaseID:	FBgn0030406	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_060423.3	Gene:	ZNHIT6 / 54680	HGNCID:	26089	Length:	470	Species:	Homo sapiens

Alignment Length:	272	Identity:	80/272 - (29%)
Similarity:	140/272 - (51%)	Gaps:	38/272 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADETSTK-----------TRTMRLGMCEVCAAKEACYACPKCEVKTCSLPCVQIHKKELNCDGQ 54
            :.|:|..|           .|.:.:..||.|..:||.|.||:|...:||||||:.||.||.|:|.
Human   193 IVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKKHKAELTCNGV 257

  Fly    55 RDRTKFVPLSEMTSREFMSDYCFLEECTRYAENRKSDP-CKRFTHDQRNLPVT---QHRMRMAAK 115
            ||:|.::.:.:.|....:|||.|||:..|.|::...|. .||        |::   .:.|:..|:
Human   258 RDKTAYISIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKR--------PISNKYMYFMKNRAR 314

  Fly   116 KRNINLRLQLENFSRHKENTTYLNWKLGRFHWRIEWLFANIPYEASLPRNVTRFVDKECNEELTL 180
            ::.|||:|....|::.|||:|:.:.|..:|.|.::..|         |::...:::|...::.|:
Human   315 RQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQF---------PQSQAEYIEKRVPDDKTI 370

  Fly   181 PDLVAKYVDLRHE--TAREQRKLLANHQTAGIGQLSFWLRAEGVRRSSTRCYLLDSTKTLAENLV 243
            .:::..|:|....  ..|::.|.....||.    :...::.|.::::..|.|.||..|:|.:||.
Human   371 NEILKPYIDPEKSDPVIRQRLKAYIRSQTG----VQILMKIEYMQQNLVRYYELDPYKSLLDNLR 431

  Fly   244 GKTIVEFPTILV 255
            .|.|:|:||:.|
Human   432 NKVIIEYPTLHV 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1463	NP_001259489.1	zf-HIT	17..43	CDD:282314	14/25 (56%)
ZNHIT6	NP_060423.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..70
ZNHIT6	NP_060423.3	zf-HIT	217..246	CDD:282314	14/28 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146337
Domainoid	1	1.000	100	1.000	Domainoid score	I7041
eggNOG	1	0.900	-	-		E1_KOG2858
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H32378
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002947
OrthoInspector	1	1.000	-	-		oto89879
orthoMCL	1	0.900	-	-		OOG6_102819
Panther	1	1.100	-	-	LDO	PTHR13483
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R130
SonicParanoid	1	1.000	-	-		X3293
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.730