Protein Alignment hwt and she

DIOPT Version :10

• Sequence 1: NP_001259484.1
• Gene: hwt / 32202
• FlyBaseID: FBgn0264542
• Length: 1768
• Species: Drosophila melanogaster
• Sequence 2: XP_689987.3
• Gene: she / 561493
• ZFINID: ZDB-GENE-090915-6
• Length: 438
• Species: Danio rerio
• Alignment Length: 580
• Identity: 130/580 - (22%)
• Similarity: 215/580 - (37%)
• Gaps: 171/580 - (29%)

  Fly  1201 PPSTNSNSNAASASASASVSATGSAAPRRPRS-FVLESGRVLELRRSAQGHQGGQSTHHHHHHHH 1264
            |.|..:.|:..   .|||.|.|.|    ||:. ..:.:|....||:::....||
Zfish     9 PTSLKTGSDRI---RSASESGTQS----RPKPVLTVGTGSKGSLRKNSGAENGG----------- 55

  Fly  1265 HAPGSRRNRHGQS-QGQTTGGGHNYSSTESIATSSSGGSMESLRSSTSEGN------------RS 1316
            ...|.....||:: :......|.|:|||.|:   ..|...|.|....|:.|            |:
Zfish    56 GGGGVGSLLHGRNRKNSAIELGRNHSSTGSM---KDGKIWEILIPGKSKKNTKMEGFEDHRTLRT 117

  Fly  1317 TSSSESRHSSSLSSHSSESGSGGSGGSGGSSVAYPLRPAPLLLHSKLHILSPISDKSSQEPASAS 1381
            ||.::...|..:..:..:|..|||......:.: |:|..|:::            :...:|..|.
Zfish   118 TSLADEYMSRMIKVNDPKSSPGGSSPDSERAKS-PIRTEPIIV------------EDYADPFDAE 169

  Fly  1382 ASEQSQQPSQQLAPMASQEDDSTTSGAPAGNQVQVNASLKQPRSNRGAPNKALLQLADELLGSDS 1446
            .:.:.::        |.:|.::.....|...|:.:....:     ||  :|.||::.
Zfish   170 KTREQKE--------AEREGENDGYMEPYDAQLIITEIRR-----RG--SKDLLKVC-------- 211

  Fly  1447 GISLHSREDGKPQALALQRLTLPKLQLIGAEGTTTSATASGAGGSSATGGSSGAGGSGSGSVVAS 1511
                                    :.|.|.||.                      |||...:.
Zfish   212 ------------------------VVLNGGEGE----------------------GSGPPQIY-- 228

  Fly  1512 GSTGIQQDLRDLPFDMPKLRRRKTLQQEAACTSGSATSVDLGELPFDMPKLRRRLRANQAEINNL 1576
             ....::.|..:|...|:...|...:.               |||::..| .:.:||..|:.:..
Zfish   229 -DVPYEEVLEGIPLTRPESDSRPPAEY---------------ELPWEWKK-EQIVRALSAQFDGA 276

  Fly  1577 LMHSTESSGISQASSSHSMRDDQKMSSKLDTALFRQNLTLNLNESRQATKQFGSLDLRGLNSNKE 1641
            ...|.|.||                           :.|:     :|.|.:..|...:.|..|..
Zfish   277 ERMSKEESG---------------------------SPTI-----KQQTLRHKSWTTKSLRPNPP 309

  Fly  1642 LNMNLSQGYVT---AVDLIDVTIPLERQGWYHGAITRIEAETTLRPLSEGSFLVRNCESTKQDYS 1703
            ...:.|...:|   ...::|.|:|||:|.||||:::|.|||..|:...|.|||||:.||....||
Zfish   310 SPTSPSSPSITPDSETPIVDPTLPLEKQSWYHGSVSRQEAEAQLQQCREASFLVRDSESATSKYS 374

  Fly  1704 LSLKGAKGFMHMRIQRNETGQYILGQFSRPFETVPEMIRHFCLNRLPVRGAEHMCLIEPV 1763
            ::||.::|.:|:.:.:.:...|.|.:.|..|.::||::.|:|..|||..|||||.|..||
Zfish   375 IALKTSQGCVHIIVAQTKECGYTLEKSSCVFPSIPEVVHHYCTQRLPFTGAEHMTLQHPV 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hwt	NP_001259484.1	SH2_SHB_SHD_SHE_SHF_like	1666..1763	CDD:198198	41/96 (43%)
she	XP_689987.3	SH2_SHE	337..434	CDD:198254	41/96 (43%)