Protein Alignment Rab40 and Rab33b

DIOPT Version :10

• Sequence 1: NP_727611.1
• Gene: Rab40 / 32195
• FlyBaseID: FBgn0030391
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_058554.1
• Gene: Rab33b / 19338
• MGIID: 1330805
• Length: 229
• Species: Mus musculus
• Alignment Length: 198
• Identity: 64/198 - (32%)
• Similarity: 105/198 - (53%)
• Gaps: 28/198 - (14%)

  Fly    11 LLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGN--DCTSHILQTVAYKTTTILLEGKRVKLQLW 73
            :.|::::|||:|||..:...         ||:|.  |.|...: .|.::...:.::|:|:|:|||
Mouse    33 IFKIIVIGDSNVGKTCLTYR---------FCAGRFPDRTEATI-GVDFRERAVDIDGERIKIQLW 87

  Fly    74 DTSGQGRF-CTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEH--APGIPKVLVGNRLHL 135
            ||:||.|| .::::.|.|....::.|||:||..||..:..|::|..:|  |..||::||||:..|
Mouse    88 DTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPAWIEECKQHLLANDIPRILVGNKCDL 152

  Fly   136 AFKRQVAAKQAETYASRNNMSCFEIS---PLCNFNIRESFCELARMALHRNGMEHIWRSNKVLSL 197
            ....||....|:.:|..::|..||.|   |..|.::...|..||          |..:|:|.|.|
Mouse   153 RSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLA----------HKLKSHKPLML 207

  Fly   198 QEL 200
            .:|
Mouse   208 SQL 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop containing Nucleoside Triphosphate Hydrolases	6..265	CDD:476819	64/198 (32%)
		SOCS	192..234	CDD:470605	4/9 (44%)
Rab33b	NP_058554.1	Rab33B_Rab33A	32..201	CDD:133315	59/187 (32%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H082	56..68		3/12 (25%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H082	89..108		7/18 (39%)