Protein Alignment Pkcdelta and PRKACB

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_891993.1
• Gene: PRKACB / 5567
• HGNCID: 9381
• Length: 398
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 119/315 - (37%)
• Similarity: 188/315 - (59%)
• Gaps: 5/315 - (1%)

  Fly  1556 PRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLAL 1620
            |...|..::||.....||.||||:|:|.:.:.|..|||:|.|.|..|::...::.||.|:::|.
Human    81 PTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ- 144

  Fly  1621 GTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKG 1685
            ....|:|..|...|:..|:|:.||||:.||::..|::..|||||..||||.|:|:...::||...
Human   145 AVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 209

  Fly  1686 IIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWS 1750
            :||||||.:|:|:|::|::::.|||..|   .:.....:.||||:|:|||||..:.||:.||||:
Human   210 LIYRDLKPENLLIDHQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 271

  Fly  1751 FGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPA 1815
            .|||:|||..|..||......:::..|.:....||.:.|::...:|:.||:.|.|||.|:..:..
Human   272 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGV 336

  Fly  1816 GDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDK 1870
            .||..|.:|...||..:.:|::|.||.|:.:...||..||. :..|.:|::..:|
Human   337 SDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDD-YEEEDIRVSITEK 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	115/301 (38%)
PRKACB	NP_891993.1	STKc_PKA	89..378	CDD:271111	114/293 (39%)