Protein Alignment Pkcdelta and PRKACA

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_001291278.1
• Gene: PRKACA / 5566
• HGNCID: 9380
• Length: 427
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 118/308 - (38%)
• Similarity: 189/308 - (61%)
• Gaps: 5/308 - (1%)

  Fly  1563 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYL 1627
            :|.|..:..||.||||:|:|.:.::|..:||:|.|.|..|::...::.||.|:::|. ....|:|
Human   117 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ-AVNFPFL 180

  Fly  1628 CHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLK 1692
            ..|..:|:..|:|:.||||:.||::..|::..|||||..||||.|:|:...::||...:||||||
Human   181 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLK 245

  Fly  1693 LDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYE 1757
            .:|:|:|.:|::::.|||..|   .:.....:.||||:|:|||||..:.||:.||||:.|||:||
Human   246 PENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYE 307

  Fly  1758 MLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHI 1822
            |..|..||......:::..|.:....||.:.|::...:|:.||:.|.|||.|:..:...||.:|.
Human   308 MAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHK 372

  Fly  1823 FFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDK 1870
            :|...||..:.:|::|.||.|:.|.|.||..||. :..|.:|::..:|
Human   373 WFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD-YEEEEIRVSINEK 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	116/301 (39%)
PRKACA	NP_001291278.1	STKc_PKA	118..407	CDD:271111	115/293 (39%)