Protein Alignment Pkcdelta and wts

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_733403.1
• Gene: wts / 43651
• FlyBaseID: FBgn0011739
• Length: 1105
• Species: Drosophila melanogaster
• Alignment Length: 1364
• Identity: 287/1364 - (21%)
• Similarity: 455/1364 - (33%)
• Gaps: 502/1364 - (36%)

  Fly   689 STSGKSETQKVPSTPLTPTVVKTNQVEAKKVESMDTSSKAPASVI--------SKAAES------ 739
            :|:|:::.       |||......|    .:|...::|.||..||        ...|.|
  Fly    50 ATNGRNDA-------LTPDYHHAKQ----PMEPPPSASPAPDVVIPPPPAIVGQPGAGSISVSGV 103

  Fly   740 ------------PKLKSATDNNK--AKPTMAKKDLPKLKTAEETKLTITTKATTATPTMDSPKTP 790
                        ||:.:|...||  .||::.:.             |.::.....:|.:||
  Fly   104 GVGVVGVANGRVPKMMTALMPNKLIRKPSIERD-------------TASSHYLRCSPALDS---- 151

  Fly   791 QAKEETSQKTESATTSQIKSDT-----------PIALQIKPQEQMKVAAPTTP-----QAKVETP 839
            .|....|....|..|.|..|.|           |     .|....:||.|..|     .....||
  Fly   152 GAGSSRSDSPHSHHTHQPSSRTVGNPGGNGGFSP-----SPSGFSEVAPPAPPPRNPTACSAATP 211

  Fly   840 PKDSP--TRKIVAPTTPQAKVETPTKDSPTRKIVTPTTPQAKVETPTKD-------------SPT 889
            |...|  ::..|...:|......|....||::..:|...|..::.|.:.             ..:
  Fly   212 PPPVPPTSQAYVKRRSPALNNRPPAIAPPTQRGNSPVITQNGLKNPQQQLTQQLKSLNLYPGGGS 276

  Fly   890 RKIVTPTTPQ-------AKVETPTKDSPTRKIVTPTTPQAKVETPTKDSPTRKIATPT---TPQA 944
            ..:|.|..|.       .....|...|.|..:.:..:|....::..:.||:..|.:.|   :|..
  Fly   277 GAVVEPPPPYLIQGGAGGAAPPPPPPSYTASMQSRQSPTQSQQSDYRKSPSSGIYSATSAGSPSP 341

  Fly   945 KAAASTTSPLTTPQKTPQVKAATDESKSTPAAPKTTMAKISMTTMAGTTVAEAGKTISPKGLKQS 1009
            ...:...:||..||  |:|..|..:......:.|:|..:                    |.:.|
  Fly   342 ITVSLPPAPLAKPQ--PRVYQARSQQPIIMQSVKSTQVQ--------------------KPVLQ- 383

  Fly  1010 GNAVAMPTATPTTPNTPTTAT-GKSKLNETAGPKINSGQPAKSPEQQQATAAAVETKINKTTDKE 1073
                     |...|.:|::|: ..|.::..|.|          |...|.:||.|:         :
  Fly   384 ---------TAVAPQSPSSASASNSPVHVLAAP----------PSYPQKSAAVVQ---------Q 420

  Fly  1074 QQQQQQQQQQQQAQQQQQQLIDTAATLVPQTETKTKLTEAAEPTGKSKVQSPNTTKPKSAGKTNV 1138
            |||......|||.|.||.:         |.|.|...|...     .||   ||..:|.|..|:..
  Fly   421 QQQAAAAAHQQQHQHQQSK---------PPTPTTPPLVGL-----NSK---PNCLEPPSYAKSMQ 468

  Fly  1139 GKKKAATPAAAAAAAAAAAPAAATATEAVTALSESNVTPINADQFITLAPTKAAKTSPNKQQALQ 1203
            .|                   |||..:                           :....:||..|
  Fly   469 AK-------------------AATVVQ---------------------------QQQQQQQQQQQ 487

  Fly  1204 LQQQHEEQQRQQQQQATNASSPAATGDATTTPTTITIGVAAVNVAAVAVVASAAAAAATDAAADA 1268
            :|||..:||:|||||.
  Fly   488 VQQQQVQQQQQQQQQQ------------------------------------------------- 503

  Fly  1269 TTSLSSNNSCGEGVGNNLSKFATVSNLAQCLRDVDAELDDYIPSSAENSQEDDDDDDDGSGSSSD 1333
                                       .|.||.:.|:      :..|..|.:.|
  Fly   504 ---------------------------LQALRVLQAQ------AQRERDQRERD----------- 524

  Fly  1334 DYSSVDGCANLSASMKKKLRKEKKKQKAKAAAAAEAKRFDPHKKIKIDTTNKCYVKEEAPRYPLV 1398
                               ::|:::.:.|.|.....::..|
  Fly   525 -------------------QRERERDQQKLANGNPGRQMLP------------------------ 546

  Fly  1399 ATPRPLWKREKIVYSDENTDDESGSEEGSGGSLDEDSDDESGGEECSSTSSSASSEDLDAVAMVT 1463
              |.|        |...|                 :::.|.....|::.:...|:.:|.....:.
  Fly   547 --PPP--------YQSNN-----------------NNNSEIKPPSCNNNNIQISNSNLATTPPIP 584

  Fly  1464 KAGSSNATTVLDSSNSSGSNAGTLSVPSAGSGSGGGASTSSSPSIIRMSTCSNDSGFEGGTAPSS 1528
            .|..:|.::...:::|.|||..|.:..|:.:........|..|...::|....:...|......|
  Fly   585 PAKYNNNSSNTGANSSGGSNGSTGTTASSSTSCKKIKHASPIPERKKISKEKEEERKEFRIRQYS 649

  Fly  1529 P---------------KKMLETSYTYSQFQKSGRFTAPATVIP-------------------RFK 1559
            |               |...:.:|..:|.:|......    :|                   |.|
  Fly   650 PQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVG----LPDQTQIEMRKMLNQKESNYIRLK 710

  Fly  1560 NYSVDDFHF--LAVLGKGSFGKVLLAELRDTT-YYYAIKCLKKDVVLEDDDVDSTLIERKVLALG 1621
            ...:|...|  |..:|.|:||:|.|....||: :.||:|.|:|..||:.:.|.....||.:||..
  Fly   711 RAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEA 775

  Fly  1622 TKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGI 1686
            ..: ::..|:.:||.:.:|:|||:|:.|||||..:.:.|.|.||.||||.||:...:..:||.|.
  Fly   776 DNN-WVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGF 839

  Fly  1687 IYRDLKLDNVLLDYEGHVRIADFGMC--------------------------------------- 1712
            |:||:|.||:|:|.:||:::.|||:|
  Fly   840 IHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPTV 904

  Fly  1713 ----KLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSG-----C 1768
                :::.:....|.|..|||:|:|||:::...|.|..|:||.||:|||||:||.||..     .
  Fly   905 LERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLET 969

  Fly  1769 DEDELFWSICNEIPWFP-VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLL 1832
            .:..:.|.....||  | ..:|.|||.:::.|. ....||:|..   ..::..|.||:.||:.
  Fly   970 QQKVINWEKTLHIP--PQAELSREATDLIRRLC-ASADKRLGKS---VDEVKSHDFFKGIDFA-- 1026

  Fly  1833 EKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMD------------QKQFHGF 1884
            :.|:.:.|:.|::|||.||..||           |:|.|.|.|.|            .:.||||
  Fly  1027 DMRKQKAPYIPEIKHPTDTSNFD-----------PVDPEKLRSNDSTMSSGDDVDQNDRTFHGF 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904	75/370 (20%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	122/377 (32%)
wts	NP_733403.1	MobB_LATS1	644..718	CDD:439273	10/77 (13%)
		STKc_LATS	717..1078	CDD:270749	121/380 (32%)