Protein Alignment Pkcdelta and Akt

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_732113.3
• Gene: Akt / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 573
• Identity: 204/573 - (35%)
• Similarity: 283/573 - (49%)
• Gaps: 101/573 - (17%)

  Fly  1410 IVYSDE---NTDDESGSEEGSGGSLDEDSDDESGGEECSSTSSSASSEDLDAVAMVTKAGSSNAT 1471
            |:||..   |:...|||.|.........|...:.....|.|.|..::.||.:.::.:....:..|
  Fly    41 IIYSQSTHPNSSPTSGSAEKFSWQQSWPSRTSAAPTHDSGTMSINTTFDLSSPSVTSGHALTEQT 105

  Fly  1472 TVLDSS-------------------NSSGSNAGTLSVPSAGSGSGGGASTSSSPS---------- 1507
            .|:...                   :|.|...|..|.|         |.::|:||
  Fly   106 QVVKEGWLMKRGEHIKNWRQRYFVLHSDGRLMGYRSKP---------ADSASTPSDFLLNNFTVR 161

  Fly  1508 ---------------IIR-----------------------------MSTCSNDSGFEGGTAPSS 1528
                           |||                             :|:...|.| |....||.
  Fly   162 GCQIMTVDRPKPFTFIIRGLQWTTVIERTFAVESELERQQWTEAIRNVSSRLIDVG-EVAMTPSE 225

  Fly  1529 PKKMLETSY-TYSQFQKSGRFTAPATVI--PRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTY 1590
            ...|.:... |.::.:.|.:|:...|..  ...|..::::|.||.|||||:||||:|...:.|..
  Fly   226 QTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAK 290

  Fly  1591 YYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFH 1655
            .||||.|||:|:::.|:|..||.|.:||. .|.||:|..|..:|||...|.|||:|:|||:|.:|
  Fly   291 LYAIKILKKEVIIQKDEVAHTLTESRVLK-STNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWH 354

  Fly  1656 IQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDK 1720
            :.....|:|:|.|||||||||.|.:||.:|||||||||:|:|||.:||:::||||:||..|...:
  Fly   355 LSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGR 419

  Fly  1721 TADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFP 1785
            |..:|||||:|:|||::....|.|.||||..||::|||:.|:.||...|.|.||..|..|...||
  Fly   420 TTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFP 484

  Fly  1786 VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLD 1850
            ..|:.||..:|.|||.||..||:|.......:|..|.||..|:|..|..::|.|||||||....|
  Fly   485 RNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTD 549

  Fly  1851 TQYFDRVFTRERVRLTPIDKE-ILASM-DQKQFHGFTY---------TNPHIT 1892
            |:|||:.||.|.|.|||.|.. .|.|: ::..|..|:|         |:.||:
  Fly   550 TRYFDKEFTGESVELTPPDPTGPLGSIAEEPLFPQFSYQGDMASTLGTSSHIS 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	159/329 (48%)
Akt	NP_732113.3	PH_PKB	105..214	CDD:269947	15/117 (13%)
		STKc_PKB	270..590	CDD:270723	158/320 (49%)