Protein Alignment Pkcdelta and Pkn3

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: XP_030107417.1
• Gene: Pkn3 / 263803
• MGIID: 2388285
• Length: 914
• Species: Mus musculus
• Alignment Length: 919
• Identity: 251/919 - (27%)
• Similarity: 379/919 - (41%)
• Gaps: 178/919 - (19%)

  Fly  1045 SGQPAKS---PEQQQATAAAVETKINKTTDKEQQQQQQQQQQQQAQQQQQQLIDTAATLVPQTET 1106
            |.:|..|   |..:|:.|...|.           ..:|.|.:.:.:|..:.:|.|.|:..|:
Mouse    93 SAEPVTSEPQPRAEQSRARLSEA-----------LHRQLQVELKVKQGAENMIHTCASGTPK--- 143

  Fly  1107 KTKLTEAAEPTGK-------------SKVQSPNTTKPKSAGKTNVGKKKAATPAAAAAAAAAAAP 1158
            :.||..||:...|             |.::|..:.:|..|.:...|..:  .|........|...
Mouse   144 ERKLLAAAQQMLKDSQLKVALLRMKISSLESSGSPEPGEASQVREGGPR--WPRLRVHLRPAGPD 206

  Fly  1159 AAA------TATEAVTALSESNVTPINADQFI----TLAPTKA-AKTSPNKQQALQLQQQ----- 1207
            ..|      ...||..|....||..:...|.:    .||..:| .:.|..|...|:|..:
Mouse   207 LLAEELQHRLRVEAAVAAGAKNVVKLLGGQRMQDRKALAEAQAQLQESSQKLDLLRLALELLLER 271

  Fly  1208 ----HEEQQRQQQQ-----------QATNASSPAATGDATTTPTTITIGVAAVNVAAVAVVASAA 1257
                |..:.|..|:           ..|.....|.||       |:.:.:.......|||...:.
Mouse   272 LPPTHSLRSRVTQELWMAMLGNPQPLGTLVKPIALTG-------TLQVRLLGCKDLLVAVPGRSP 329

  Fly  1258 AAAATDAAADATTSLSSNNSCGEG-VGNNLSKFATVSN--LAQCLRDVDAE--LDDYIPSSAENS 1317
            .|....:.:::.....|....|.| :.:.:.....|.|  :.|....:.||  .|.....|.:.:
Mouse   330 MAVLAGSPSESWLRTRSRQQRGGGELASEVLAVLKVDNRVVGQTGWGLVAEKSWDQSFIISLDRA 394

  Fly  1318 QEDDDDDDDGSGSSSDDYSSVDG-------------CANLSASMKKKLRKEKKKQKAKAAAAAEA 1369
            :|.:      .|....|:..:.|             |..||.|:..:.|           ..|:.
Mouse   395 RELE------IGVHWRDWRQLCGVAFLKLEDFLDNACHQLSLSLVPQGR-----------LFAQV 442

  Fly  1370 KRFDPHKKIKIDTTNKCYVKEEAPRYPLVATPRPLWKREKIVYSDENTDDESGSEEGSGGSLDED 1434
            ...:|                       |...||..:|::.::|.....|..
Mouse   443 TFCEP-----------------------VIERRPRLQRQRCIFSKRRGRDFM------------- 471

  Fly  1435 SDDESGGEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLDSSNSSGSNAGTLSVPSAGSGSGGG 1499
                    ..|..:.|.::.....::::....|.| |........|.:..||   |||.|.|
Mouse   472 --------RASQMNLSMAAWGRLVMSLLPPCSSPN-TASPPKGRPSTAVCGT---PSAASPS--- 521

  Fly  1500 ASTSSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETSYTYSQFQKSGRFTAPATVIPRFKNYS-- 1562
                   :.:.|.|.|.:   :....|..|:..|:.....:...|.........|:|.....|
Mouse   522 -------NFLPMKTLSKE---DTKPPPKPPRLYLQEPAPGTPCTKRPHMDPRPAVVPALAALSTR 576

  Fly  1563 ----VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVL-ALG- 1621
                :.||..|||||:|.||||||.:.:.|..|||||.|||..||..|::||...|:::| .:|
Mouse   577 KPPRLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVGR 641

  Fly  1622 TKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGI 1686
            |.||:|..|....||.||..||.|:|.|||||..|.|. .|.|.:|.||.|.::.||:|||:|.|
Mouse   642 TGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQIHED-VFPEPQACFYLACVVLGLQFLHEKRI 705

  Fly  1687 IYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSF 1751
            |||||||||:|||.:|.::|||||:||..|.......:|||||:::|||::..|.|.:.||||..
Mouse   706 IYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGL 770

  Fly  1752 GVLLYEMLIGQSPFSGCDEDELFWSICN-EIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPA 1815
            ||||||||:|:.||.|..|:|:|..|.: ::| .|.::|.:...:::.||:|...||:|:....|
Mouse   771 GVLLYEMLVGECPFPGDTEEEVFECIVSADVP-CPHFLSVQGLELIQKLLQKSPEKRLGAGERDA 834

  Fly  1816 GDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLT-PIDKEILASMDQK 1879
            .:|....|||..:|..|..|.::|||.|.:..|.|.:||:..||.....|| |:.:..|.:..|.
Mouse   835 EEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVSQSSLTARQQA 899

  Fly  1880 QFHGFTYTN 1888
            .|..|.:.:
Mouse   900 AFRDFDFVS 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904	21/101 (21%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	146/323 (45%)
Pkn3	XP_030107417.1	HR1_PKN_1	23..88	CDD:212012
		HR1	103..176	CDD:469609	18/86 (21%)
		HR1	203..>257	CDD:469609	12/53 (23%)
		C2	357..444	CDD:472691	17/103 (17%)
		STKc_PKN	584..909	CDD:270741	148/327 (45%)