Protein Alignment Pkcdelta and C56G2.5

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_498384.2
• Gene: C56G2.5 / 183867
• WormBaseID: WBGene00016980
• Length: 713
• Species: Caenorhabditis elegans
• Alignment Length: 655
• Identity: 160/655 - (24%)
• Similarity: 256/655 - (39%)
• Gaps: 150/655 - (22%)

  Fly  1271 SLSSNNSCGEGVGNNLSKFATVSN-----LAQCLRDVDAELDDYIPSSAENSQEDDDDDDDGSGS 1330
            ||..:.|..|.|.....:...|.|     |:.|....::.|   .|.|...|:        |..|
 Worm   124 SLRKDESPNEKVLRETEQTILVLNEKLDLLSNCCSQKESSL---TPISVRRSR--------GGPS 177

  Fly  1331 SSDDYS-SVDGCANLSASMKKKLRKEKKKQKAKAAAAAEAKRFDPHKKIKIDTTNKCYVKEEAPR 1394
            .::::. :|.|...:..:....|....|.:..:.|:...|:.....|.:        :.:....|
 Worm   178 KTNNFPVAVSGFLKIRVTGLADLPNNTKHRSGRYASEHFAQLIKKKKSM--------FGRHGFRR 234

  Fly  1395 YP------------------LVATPRPLWKREK-IVYSDENTDDESGSEEGSGGSLDEDSDDESG 1440
            ||                  .|||  .:|..:| :|..||.|.....|.:     ||.:......
 Worm   235 YPNRSSAVNDYIIVIHVGGKEVAT--MVWNEKKTMVGGDEETIQLFKSRQ-----LDFEIYHTDS 292

  Fly  1441 GEECSSTSSSASS--EDLDA-----------VAMVTKAGSSNATTVLDSSNSSGSNAG------- 1485
            ...|:..|....|  ::.||           |.::.:......||..|...|.....|
 Worm   293 RSLCAIGSMQLESLLDEHDAKFPFATFAHRVVNLIPEGTLHFQTTYSDPEQSMEKKLGDTCTDGV 357

  Fly  1486 ---TLSVPSAGSGSGGGASTSSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETSYTYSQFQKSGR 1547
               .:|:..:||....|:.|..||                           .|:.:.:||
 Worm   358 SKLAVSMRKSGSVLARGSKTFYSP---------------------------RTAISLNQF----- 390

  Fly  1548 FTAPATVIPRFKNY-----SVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDD 1607
              .|.|  |..|:.     |:|.:..::.:|.|:||.|.|.:......|.|||.::||......|
 Worm   391 --VPLT--PSMKSRTRRIDSLDSYRLISEIGVGAFGTVKLGQRIHDNMYCAIKIIEKDPRTRSFD 451

  Fly  1608 VDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGR-FSEERARFYG 1671
            .....| .|||    .||::|.|..:|..:..|:.|:|:...|||..|:..:.. |::::..|:.
 Worm   452 TPELHI-LKVL----HHPFICSLIASFIEKDALYLVLEFCEAGDLHTHLSRTAHGFTKKQVTFFA 511

  Fly  1672 AEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFC---GTPDYMA 1733
            |.|:..:::||:|...:||||.:|::|..||.::|.|||:||   .|....|..|   ||..::|
 Worm   512 ASIVLAVEYLHEKLYCHRDLKTENMMLTREGVLKIIDFGLCK---RLSSREDKMCDIVGTTTHLA 573

  Fly  1734 PEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDEL-------FWSICNEIPWFPVYISAE 1791
            .||.:.|.|..::|||:.||.||::...:.||.|..|.|:       .|.|.|:
 Worm   574 AEIFRREPYGISMDWWAVGVSLYQLRTREQPFYGTREVEMEKNSRVREWHIFND----------- 627

  Fly  1792 ATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDR 1856
               :|.||:......|:|  |....|:..|.||...|:..:....|.||:.|.:|..||.:||:.
 Worm   628 ---LLIGLMANHPEARLG--YHSTEDVKKHPFFMDTDFDAVLNSAIPPPYVPLLKPGLDLEYFEH 687

  Fly  1857 VFTRE 1861
            .:..|
 Worm   688 QYHSE 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	96/303 (32%)
C56G2.5	NP_498384.2	S_TKc	410..655	CDD:214567	83/268 (31%)