DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pkcdelta and tpa-1

DIOPT Version :10

Sequence 1:NP_572797.3 Gene:Pkcdelta / 32191 FlyBaseID:FBgn0287828 Length:1894 Species:Drosophila melanogaster
Sequence 2:NP_001379590.1 Gene:tpa-1 / 176825 WormBaseID:WBGene00006599 Length:704 Species:Caenorhabditis elegans


Alignment Length:428 Identity:212/428 - (49%)
Similarity:274/428 - (64%) Gaps:20/428 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly  1477 SNSSGSNAGTLSVPSAGSGSGGGASTSSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETSYTYS- 1540
            ||..|.|...||........|..|:.|..|:|..:. .:.::....|:.|:..|.:.: |:.|| 
 Worm   284 SNLCGVNQKQLSEMYHEIKRGTHATASCPPNIANLH-LNGETSKNNGSLPNKLKNLFK-SHQYSV 346

  Fly  1541 QFQKS---------GRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKC 1596
            :.||.         |....|.      |.:::..|:.|.||||||||||:|.||:....:||:||
 Worm   347 EEQKETDEYMDNIWGGGDGPV------KKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKC 405

  Fly  1597 LKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGR 1661
            |||||:|||||.:.|.|||:||.|.::.|:||.|||:|||..:||||||||||||||.|||:..:
 Worm   406 LKKDVILEDDDTECTYIERRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKK 470

  Fly  1662 FSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDK-TADSF 1725
            |.|.|.|||..||:..|:|||...||||||||||||||.:||:::|||||.|.::..:. .|.:|
 Worm   471 FDEARTRFYACEIVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTF 535

  Fly  1726 CGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISA 1790
            ||||||::||||||:.||:.||:||||||:||||:|||||.|..|||||.||.||.|:||..||.
 Worm   536 CGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISK 600

  Fly  1791 EATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFD 1855
            ||...|..|.:::...|:|....|.|.|..|.|||.:||...|.||:.|||||.:|...|...||
 Worm   601 EAAKCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFD 665

  Fly  1856 RVFTRERVRLTPI-DKEILASMDQKQFHGFTYTNPHIT 1892
            ..||.|:..|||: ||.:|||:|.:.|..|:|||||.:
 Worm   666 DDFTNEKAALTPVHDKNLLASIDPEAFLNFSYTNPHFS 703

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PkcdeltaNP_572797.3 Herpes_BLLF1 <802..1131 CDD:282904
STKc_nPKC_theta_like 1570..1889 CDD:270744 185/320 (58%)
tpa-1NP_001379590.1 C1_nPKC_theta-like_rpt1 159..219 CDD:410384
C1_nPKC_theta-like_rpt2 238..287 CDD:410387 2/2 (100%)
STKc_nPKC_theta_like 379..700 CDD:270744 185/320 (58%)
Blue background indicates that the domain is not in the aligned region.

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