Protein Alignment Pkcdelta and LOC1274280

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: XP_061506799.1
• Gene: LOC1274280 / 1274280
• VectorBaseID: AGAMI1_009005
• Length: 1394
• Species: Anopheles gambiae
• Alignment Length: 1563
• Identity: 330/1563 - (21%)
• Similarity: 514/1563 - (32%)
• Gaps: 581/1563 - (37%)

  Fly   727 KAPASVISKAAESPKLKSATDNNKAKPTMAKKDLPKLKTAEET------KLTITTKATTATPTM- 784
            |.|.||...:|          .|.......|.:|...:|:::.      :|....|   ..|::
Mosquito     7 KVPLSVARHSA----------YNAIALEQIKNELQPYETSQQALGGGGGQLVAPLK---RKPSIE 58

  Fly   785 -DSPKTPQAKEETSQKTESATTSQIKSDTPIALQIKPQEQMKVAAPTTPQAKVETPPKDSPTRKI 848
             |:|::|...:.||...:|...|. :|::       |..|...:|........:..|...||...
Mosquito    59 KDAPQSPLHMQRTSPALDSGAGSS-RSNS-------PHSQQPFSAAHVVGRSSQYSPSPCPTNFS 115

  Fly   849 VAPTTPQAKVETPTKDSPTRKIVTPTTPQ--------------------------AKVETPTKDS 887
            .||..|           |.|...||:|||                          |..::|.:.|
Mosquito   116 DAPPIP-----------PPRCSSTPSTPQPPNPMHLLKRMSPASVASGRNGQFGGAASQSPARGS 169

  Fly   888 P-----------TRKIVTPTTPQAK--------VETPTKDSPTRKIVTPTTP----------QAK 923
            .           .:.|:....||.:        |.|..:..|....:.|::|          |:.
Mosquito   170 SPIASSGNHPGLRQPIIVQNGPQVQQQLSQQMAVYTGNEPPPPYPQLGPSSPPNYLTSFHSRQSP 234

  Fly   924 VETPTKDSPTRKIATPTTP-QAKAAASTTSPLTTPQ----------------KTPQVKAATDESK 971
            .::.:..|..||  :|::. .:.|:..::||:|..|                :.|........:.
Mosquito   235 TQSSSAQSDFRK--SPSSGFYSNASIGSSSPITVSQGAGGGGGGSGLLGAAIQRPIPLQPKPSAV 297

  Fly   972 STPAAPKTTMAKISMTTMAGTTVAEAGKTISPKGLKQSGNAVAMPTATPTTPNTPTTATGKSKLN 1036
            ..||: |.....|.|.::..|.|        .|.:.|:..|.|.|..     ..|.|:.|...
Mosquito   298 HAPAS-KAAQHPIIMHSVKSTQV--------QKPILQTAVAPAAPAG-----GVPGTSGGSGG-- 346

  Fly  1037 ETAGPKINSGQPAKSPEQQQATAAAVETKINKTTDKEQQQQQQQQQQQQAQQQQQQLIDTAATLV 1101
                   ..|.|..:.....:.|.:|:.|:||..
Mosquito   347 -------GGGHPLHNNPPPPSYAVSVQAKLNKAA------------------------------- 373

  Fly  1102 PQTETKTKLTEAAEPTGKSKVQSPNTTKPKSAGKTNVGKKKAATPAAAAAAAAAAAPAAATATEA 1166
                              |...:|....|.:.|....|   |.....|||:|||..|.:....:.
Mosquito   374 ------------------SGYATPPPPSPSALGHEGGG---AGRHVGAAASAAAGGPGSGVPKQP 417

  Fly  1167 VTALSE----SNVTPINADQFITLAP---------------TKAAKTSPNKQQALQ--------- 1203
            :.|...    .||.|.|       .|               |...::||.:.|||.
Mosquito   418 LRAKPSLPGLQNVLPSN-------VPVQTVGGGGGGGVGGGTMNGQSSPAQPQALSGSSNNGVSS 475

  Fly  1204 ------------------LQQQH-----------------------------------EEQQRQQ 1215
                              |.|:|                                   |.:|:||
Mosquito   476 GSSTGSPNDPPSYDTTMILLQKHSSPKKEPPPAYLLDGGGGGTPPPLPPSPHCPPSAMEMEQQQQ 540

  Fly  1216 QQQATNASS------------------------------PAATGDATTTPTTITIGVAAVNVAAV 1250
            ||...|..:                              ....|:|.        |...||..|
Mosquito   541 QQHRNNGGNNHHQQSYQHQQLQHHHHHLNHHNHLLHHQHHNGHGNAD--------GGGMVNGNA- 596

  Fly  1251 AVVASAAAAAATDAAADATTSLSSNNSCGEGVGNNLSKFATVSNLAQCLRDV----DAELDDY-- 1309
               .....:....::..:|...||:|:....:..|:|..|..:|....:..:    :....|:
Mosquito   597 ---NGGGGSGMNQSSNSSTNGSSSHNANANTINGNMSNNANANNNNNTMNSMHNNNNHNNHDHAM 658

  Fly  1310 -------------IPSSAENSQEDDDDD----------------------------DDGSGSSSD 1333
                         :|.|..:...|||..                            ...||::..
Mosquito   659 MHGGSSIVSNGKVVPPSGLSRTVDDDRHHHHLHPHATNGLMQQHPADPKPKAPHKLSGSSGAAQH 723

  Fly  1334 DYSSV---------DGCANLSASMKKKLRKEKKKQKAK-----------AAAAAEAKRFDPHKKI 1378
            .:|..         .|....|...:::|..:..:|:.:           :.||:...|....|.:
Mosquito   724 TFSGALKTLGALMGGGQQQQSQQQQQQLNHQHHQQQQQQQHDAKQRGIASTAASGGVRSSLMKSV 788

  Fly  1379 KI-----DTTNKCYVKEEAPRYPLVATPRPLWKREKIVYSDENTDDESGSEEG--SGGSLDEDS- 1435
            :.     :|.|    ...||.|                     |:...|.:.|  ||.|..|.|
Mosquito   789 RFPGTGGNTNN----NGPAPAY---------------------TNGGGGMDHGTPSGSSTAESSP 828

  Fly  1436 ----DDESGGEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLDSSNSSGSNAGTLSVPSAGSGS 1496
                ...|||.    |||.......:|.:.|. :|..||:|...||:..||.||..:...|| ||
Mosquito   829 ATTPTSASGGR----TSSGGGGGGAEAGSSVA-SGVGNASTSGASSSGGGSAAGGAAGGGAG-GS 887

  Fly  1497 GGGASTSSSPSIIR-------MSTCSNDSGFEGGT------APSSPKKMLE-------TSYTYSQ 1541
            |||.....:|..|:       ....|.:...|...      :|.:.|..:|       .||:...
Mosquito   888 GGGGGGEDNPRKIKHQSPIPERKNLSKEKEAERSECKVKHYSPQAYKFFMEQHIENVLKSYSQRN 952

  Fly  1542 F---------------------------QKSGRFTAPATVIPRFKNYSVDDFHF--LAVLGKGSF 1577
            |                           ||...:.       |.|...:|...|  :..:|.|:|
Mosquito   953 FRIKQLESEMSKLDLPEETKIEMRKLLCQKESNYI-------RLKRAKMDKSMFAKIKTIGVGAF 1010

  Fly  1578 GKVLLAELRDTT-YYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLF 1641
            |:|.|.:..||| :.||:|.|:|..||:.:.|.....||.:|| ...:.::..|:.:||.:.:|:
Mosquito  1011 GEVTLVKKIDTTNHLYAMKTLRKADVLKRNQVAHVKAERDILA-EADNEWVVKLYYSFQDKDNLY 1074

  Fly  1642 FVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRI 1706
            |||:|:.|||||..:.:.|.|.|:.||||.||:...:..:||.|.|:||:|.||||:|.:||:::
Mosquito  1075 FVMDYIPGGDLMSLLIKKGIFEEDLARFYIAELTCAIDSVHKMGFIHRDIKPDNVLIDRKGHIKL 1139

  Fly  1707 ADFGMC-------------------------------------KLQIYLDKT---ADSFCGTPDY 1731
            .|||:|                                     :.:.:.:|.   |.|..|||:|
Mosquito  1140 TDFGLCTGFRWTHDSKYYQKNDHARQDSMEAWSKFGPDIPPPLERRKFREKNRAKAHSIVGTPNY 1204

  Fly  1732 MAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPW-----FPV--YIS 1789
            :|||::....|.|..||||.||:|||||:||.||.....:|....:.|   |     .||  :::
Mosquito  1205 IAPEVLMRSGYTQLCDWWSVGVILYEMLVGQPPFLANTAEETQIKVIN---WRQTLRIPVDAHLT 1266

  Fly  1790 AEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYF 1854
            .||..|:..|. |:..:|||..   ..:|..|.|||.||: ..:.|..:..::|::|:|.||..|
Mosquito  1267 PEAMDIILRLC-KNEDERIGRN---VDEIKSHPFFRTIDF-TKDLRSQQALYEPKIKYPTDTSNF 1326

  Fly  1855 DRVFTRERVRLTPID----KEILASMDQ-------------KQFH----GFTY-------TNPHI 1891
            |           |||    ::..:|.|:             |.||    .||:       .:..|
Mosquito  1327 D-----------PIDPGRLQDSSSSCDENGHGNLDEVCDSGKPFHHGFFEFTFRRFFDDECDHKI 1380

  Fly  1892 TLD 1894
            |||
Mosquito  1381 TLD 1383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904	65/400 (16%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	126/394 (32%)
LOC1274280	XP_061506799.1	None