DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uch-L5R and uch2

DIOPT Version :9

Sequence 1:	NP_572781.1	Gene:	Uch-L5R / 32173	FlyBaseID:	FBgn0030370	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_595456.1	Gene:	uch2 / 2540956	PomBaseID:	SPBC409.06	Length:	300	Species:	Schizosaccharomyces pombe

Alignment Length:	308	Identity:	125/308 - (40%)
Similarity:	173/308 - (56%)	Gaps:	39/308 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NWCLIESDPGVFTEMISGFGCTGAEVEEIWSIKADAFRHLEPIHGLIFLFKWLD--DKPAGRVVT 86
            :|..||||.||||::|...|....||:|::|:..|:.|....|:|:||||||..  |||.|.:..
pombe     2 SWTTIESDAGVFTDLIENLGVKDVEVDELYSLDVDSLRQFPDIYGIIFLFKWNSKVDKPDGTMDY 66

  Fly    87 DRSD-IFFARQVIPNACATQALLCLLLNLQHED-IDLGQTLTDLRNLCQDLDPECRGHRLANEEK 149
            |..| ||||:|||.|||||||||.:|||  |.| ||||.||::.::..:.|.||.:|..|.|.|.
pombe    67 DSMDNIFFAKQVINNACATQALLSVLLN--HSDEIDLGTTLSEFKDFSKTLPPELKGEALGNSEH 129

  Fly   150 IRKVHNSFARPELFVVEE---STDFIEDDCYHFVGFMPIKGKLFELDGMHEGPIELADIDQQQNW 211
            ||..||||||.:.|:.||   :||  ||:.|||:.:..|....:||||:...||......::: :
pombe   130 IRCCHNSFARSDPFISEEVRAATD--EDEVYHFIAYTNINNVFYELDGLQAAPINHGSCTKEE-F 191

  Fly   212 LDVVRPIIEARMERYSVGEIHFNLMALVSDRQRCYERKIQMLVNLPSQLSHADRQAEIANLRSHV 276
            .:....:|:||:..|...||.||||.:      |.::|..:|..  ..|:..::.|.||
pombe   192 AEKAVSVIQARIANYDPAEIRFNLMVI------CKDKKASLLTR--EDLTDEEKAASIA------ 242

  Fly   277 RHEKEKKRRYRKENIRRRHNYLPFIVELLKQLGETGQLMAICDKAKDR 324
             .|.||:.|:::||..||||::...|||.|.|            .|||
pombe   243 -VEDEKRLRWKRENQLRRHNFVGLFVELSKLL------------VKDR 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uch-L5R	NP_572781.1	Peptidase_C12_UCH37_BAP1	25..238	CDD:187738	100/219 (46%)
uch2	NP_595456.1	Peptidase_C12_UCH37_BAP1	3..218	CDD:187738	100/219 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	167	1.000	Domainoid score	I927
eggNOG	1	0.900	-	-		E1_KOG2778
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H137906
Inparanoid	1	1.050	201	1.000	Inparanoid score	I992
OMA	1	1.010	-	-		QHG53985
OrthoFinder	1	1.000	-	-		FOG0001783
OrthoInspector	1	1.000	-	-		otm46989
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10589
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1589
SonicParanoid	1	1.000	-	-		X1137
TreeFam	1	0.960	-	-
	13	12.960