Protein Alignment Cyp318a1 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 457
• Identity: 109/457 - (23%)
• Similarity: 180/457 - (39%)
• Gaps: 104/457 - (22%)

  Fly    81 LLYIDDPAGMECVLNAPECLDKTFLQDGFFVR-------RGLLHARGQKWKLRRKQLNPAFSHNI 138
            ::.|..||.::.|:.||..:..   :|..|.|       .|||.:.|.||...|:.|.|||..||
Mouse    98 VIRIFHPAFIKPVVLAPALVAP---KDTVFYRFLKPWLGDGLLMSTGDKWSRHRRMLTPAFHFNI 159

  Fly   139 VASFFDVFNSVGNQMVEQFQTQTNLHGQA-------VKFTAAEDLLS-----------------R 179
            :..:..|||...|.|..::|...: .|.|       :.....:.|..                 .
Mouse   160 LKPYVKVFNDSTNIMHAKWQRLAS-KGSAYLNMFEHISLMTLDSLQKCVFSFDSNCQEKPSEYIT 223

  Fly   180 AVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRLLAPELYEESKKC 244
            |:||:|.|                :|..::|||           |.:.|.:.|....:  ..:|.
Mouse   224 AILELSTL----------------VARRHQRLL-----------LHVDLFYYLTHDGM--RFRKA 259

  Fly   245 AKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANGE-----MTLEE 304
            .:|:.||...::|.:.|.  |.|     :.|.|......:...::.|..|..:.:     ::.|:
Mouse   260 CRLVHDFTDAVIRERRRT--LLD-----QGGVDVLKAKAKAKTLDFIDVLLLSKDEHGKALSDED 317

  Fly   305 IMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPD--VGQVGLEQLQQLRYL 367
            |..||.:.:....:|.::.:...|..||.:. :.|.|...|:|.|:.|  ..::..:.|.||.:|
Mouse   318 IRAEADTFMFGGHDTTASGLSWILYNLARHP-EYQERCRQEVRELLRDREPEEIEWDDLAQLPFL 381

  Fly   368 DAFVSESLRLLATVPMNLRHVSRDFRLA-GRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFD 431
            ...:.|||||...|....|..::|..|. ||    ::|:..|..:..|....:...| .:...:|
Mouse   382 TMCIKESLRLHPPVTAISRCCTQDIVLPDGR----VIPKGVISRISIFGTHHNPAVW-PDPEVYD 441

  Fly   432 PQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLIT 496
            |.||           ..|:..|        |...:|:|||.|.|:|||:.:.:..|||.|...:.
Mouse   442 PFRF-----------DADNVKG--------RSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLL 487

  Fly   497 NF 498
            .|
Mouse   488 RF 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	109/457 (24%)
Cyp4f18	NP_077764.2	CYP4F	74..515	CDD:410772	109/457 (24%)