Protein Alignment: Tango4 and prp5

• Sequence 1: NP_572778.1
• Gene: Tango4
• FlyBaseID: FBgn0030365
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_595604.1
• Gene: prp5
• PomBaseID: SPBP22H7.07
• Length: 473
• Species: Schizosaccharomyces pombe
• Alignment Length: 475
• Identity: 248/476 (52%)
• Similarity: 327/476 (69%)
• Gaps: 20/476 (4%)

  Fly    11 VHTLIFRSLKRTHDLFVSNQGNLPEIDERL-EKLRRSIKAKDGYGLVLDKVAKIGEARKASGAQ- 73
            |.:|...||:.:..||.:..|::...|:.: :.|:|:.|....||.||.  ..:|:.:.....:
pombe    13 VLSLTTNSLRTSKTLFGAEFGSVTSFDDTVAQNLKRTYKEHLEYGSVLG--GTVGKRKNRHYEED 75

  Fly    74 TPGDKTLAITDGSATDAASGAGSLVKYNAGARPAEKTAPLVTGTHTSLVRASLANSNADMSANGA 138
            |.|...|.:...|...::.   .:.|:   :.|.:|.|..|:       ..||........|...
pombe    76 TIGSNALTVRADSENPSSQ---VITKF---SDPNKKIAGQVS-------MQSLEKIKGVPEAAHR 127

  Fly   139 IA--SHLQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDL 201
            ||  |...|:.:......:|:|||||.|.||||||||||||:.|||||:||.||||||.||||||
pombe   128 IAGESQASLVKRTLAEQIRPEWHAPWTLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDL 192

  Fly   202 ASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHP 266
            |||.|||:||||::||||:|||.:||||||||||:.|||||||.||||||||||||.||:|.|||
pombe   193 ASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHP 257

  Fly   267 TIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGK 331
            |:|||.|:|||:.||:|||||:.|||.|:||.:||||:..|..:||::|||.|||:|||||||||
pombe   258 TLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGK 322

  Fly   332 SVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLV 396
            ::.|||:|||:||::.|||..:.|||.|.||||.|:.|||.|:.|..||.:|||.::.||:.|:.
pombe   323 TLTTLTHHKKTVRALSLHPDEFTFASGSSDNIKHWKFPEGAFMGNFEGHNAIVNTLSINSDNVMF 387

  Fly   397 SGGDNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDD 461
            ||.|||:|.||||::|:.:|..|:.|||||:||||||||..||::|.||||.||||::|:||:.|
pombe   388 SGADNGSMCFWDWKSGHKYQELQSVVQPGSLDSEAGIFASSFDKTGLRLITCEADKSVKIYKQVD 452

  Fly   462 EASEESHP-INWRPDLLKRR 480
            .|:.|:|| :.|.|..|:||
pombe   453 NATPETHPNLPWTPSNLRRR 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	<161..458	CDD:225201	201/297 (68%)
		WD40	164..458	CDD:238121	199/294 (68%)
		WD40 repeat	177..212	CDD:293791	28/35 (80%)
		WD40 repeat	218..254	CDD:293791	30/36 (83%)
		WD40 repeat	259..295	CDD:293791	25/36 (69%)
		WD40 repeat	302..337	CDD:293791	22/35 (63%)
		WD40 repeat	343..378	CDD:293791	19/35 (54%)
		WD40 repeat	386..426	CDD:293791	20/40 (50%)
		WD40 repeat	433..457	CDD:293791	15/24 (63%)
prp5	NP_595604.1	WD40	<143..402	CDD:225201	176/259 (68%)
		WD40	155..449	CDD:238121	199/294 (68%)
		WD40 repeat	168..203	CDD:293791	28/35 (80%)
		WD40 repeat	209..245	CDD:293791	30/36 (83%)
		WD40 repeat	250..286	CDD:293791	25/36 (69%)
		WD40 repeat	293..328	CDD:293791	22/35 (63%)
		WD40 repeat	334..369	CDD:293791	19/35 (54%)
		WD40 repeat	375..414	CDD:293791	19/39 (49%)
		WD40 repeat	424..448	CDD:293791	15/24 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	1	1.000
Homologene	1	1.000				H2004
Inparanoid	1	1.050	489	1.000	Inparanoid score	I253
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0003511
OrthoInspector	1	1.000				T1125809
orthoMCL	1	0.900				OOG5_128222
Panther	1	1.100			LDO	PTHR19923
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R995
TreeFam	1	0.960
	11	10.960