Protein Alignment Tango4 and plrg1

DIOPT Version :10

• Sequence 1: NP_572778.1
• Gene: Tango4 / 32168
• FlyBaseID: FBgn0030365
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_998605.1
• Gene: plrg1 / 100004402
• ZFINID: ZDB-GENE-040426-2787
• Length: 511
• Species: Danio rerio
• Alignment Length: 533
• Identity: 309/533 - (57%)
• Similarity: 366/533 - (68%)
• Gaps: 78/533 - (14%)

  Fly     4 EDVQKHSVHTLIFRSLKRTHDLFVSNQGNLPEIDERLEKLRRSIKAKDGYGLVLD-KVAKIGEAR 67
            |||||||||||:|||||||||:||::.......||:..|::.:.|.:..|..||. .|.|.|..:
Zfish     3 EDVQKHSVHTLVFRSLKRTHDMFVADHAKPIAQDEQSFKVKMAAKMRAEYKAVLHMPVLKEGREK 67

  Fly    68 KASGAQTPGDKTLAITDGSATDAASGAGSLVKYNAGARPAEKTAP--LVTGTH------------ 118
            .:.....|                        |...|.|...|.|  ||||||
Zfish    68 GSLHTSDP------------------------YGQSAYPLPDTTPEYLVTGTHPYPSAPGVVLTA 108

  Fly   119 ---------------------TSLVRASLANSNADMS-----ANGAIASH-------------LQ 144
                                 .|..|...:.:.|.::     |.||..||             ..
Zfish   109 DTQMLKMPSEMGVHSMALALPPSQARQEASRTAASVAEIHRHAGGAERSHPPQHALSLMEGGTRT 173

  Fly   145 LIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLS 209
            |:|:|||::|||:||.||||.|||||||||||.|||||||:||.||:.||.||||||||||||||
Zfish   174 LVPRKAPTMPKPQWHPPWKLYRVISGHLGWVRSIAVEPGNQWFVTGSADRTIKIWDLASGKLKLS 238

  Fly   210 LTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATS 274
            ||||:|||||||||.:.|||||||||:||||||||||||||||||||||||.|.||||||||.|.
Zfish   239 LTGHISTVRGVAVSNRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYDLDLHPTIDVLVTC 303

  Fly   275 GRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNH 339
            .||:|||:||:|||||||||:|||||||:|..|:..||::|||||:|:|||||.|||:..|||||
Zfish   304 SRDATARVWDIRTKANVHTLSGHTNTVATVKCQSAEPQVVTGSHDTTIRLWDLVAGKTRATLTNH 368

  Fly   340 KKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLVSGGDNGTM 404
            |||||::||||..|.|||.||||||||:.|:|.|:||:|||.:|:|.:|.||:||||||.||||:
Zfish   369 KKSVRALVLHPRQYTFASGSPDNIKQWKFPDGNFIQNLSGHNAIINTLAVNSDGVLVSGADNGTI 433

  Fly   405 FFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDDEASEESHP 469
            ..|||||||||||..|.|||||:|||:|||:..||||.|||||||||||||||||||.|:|||||
Zfish   434 HMWDWRTGYNFQRIHAAVQPGSLDSESGIFSCVFDQSESRLITAEADKTIKVYKEDDTATEESHP 498

  Fly   470 INWRPDLLKRRKF 482
            :||:|::|||::|
Zfish   499 VNWKPEILKRKRF 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango4	NP_572778.1	WD40	164..458	CDD:238121	226/293 (77%)
		WD40 repeat	177..212	CDD:293791	28/34 (82%)
		WD40 repeat	218..254	CDD:293791	31/35 (89%)
		WD40 repeat	259..295	CDD:293791	27/35 (77%)
		WD40 repeat	302..337	CDD:293791	20/34 (59%)
		WD40 repeat	343..378	CDD:293791	23/34 (68%)
		WD40 repeat	386..426	CDD:293791	28/39 (72%)
		WD40 repeat	433..457	CDD:293791	19/23 (83%)
plrg1	NP_998605.1	WD40	193..487	CDD:238121	226/293 (77%)
		WD40 repeat	206..241	CDD:293791	28/34 (82%)
		WD40 repeat	247..283	CDD:293791	31/35 (89%)
		WD40 repeat	288..324	CDD:293791	27/35 (77%)
		WD40 repeat	331..366	CDD:293791	20/34 (59%)
		WD40 repeat	372..407	CDD:293791	23/34 (68%)
		WD40 repeat	413..451	CDD:293791	26/37 (70%)
		WD40 repeat	462..486	CDD:293791	19/23 (83%)