Protein Alignment Pdzd8 and Pdzd8

DIOPT Version :10

• Sequence 1: NP_572771.1
• Gene: Pdzd8 / 32157
• FlyBaseID: FBgn0030358
• Length: 1037
• Species: Drosophila melanogaster
• Sequence 2: XP_061519836.1
• Gene: Pdzd8 / 1273392
• VectorBaseID: AGAMI1_013968
• Length: 1074
• Species: Anopheles gambiae
• Alignment Length: 1156
• Identity: 494/1156 - (42%)
• Similarity: 670/1156 - (57%)
• Gaps: 219/1156 - (18%)

  Fly     7 NILLLCLIFLLIGGVVMILLQYLIFIKFSNLPD---ESEEQKQA--NAKYTLPLNIKQTARNLKR 66
            |:||.||:..:||.|||:|:||..|:::..||:   |.|.|:::  :.:|.||..:.:   |:|
Mosquito     5 NLLLFCLMSCVIGAVVMLLIQYYAFVRYFRLPELHQEEENQRKSAFSERYVLPDTLLE---NIK- 65

  Fly    67 LSNSGLGGGAGNGCENHQESLRRASALVSLNFVMQFLFHEFKNSNRVRKWFYRKLSIELDELISK 131
                          ...|||   .|.::::|.::|||:.|.:.||||||||:||||:||||||||
Mosquito    66 --------------APDQES---KSTIMAINLILQFLYFELRQSNRVRKWFHRKLSLELDELISK 113

  Fly   132 TTTGKLLDKLTIKELELGDQFPDVKSLSVHNVELDKDEQRIENLDLLLDINYVGNFTTSIDADMV 196
            ||||||.|||||::|:||.|||::|:..:|.|:|..||..||:||:|||::|.|||..:||||||
Mosquito   114 TTTGKLFDKLTIRDLDLGSQFPEIKNFRLHAVDLHPDEGHIESLDVLLDLHYEGNFRLTIDADMV 178

  Fly   197 LGKKGSITLRVKQLSGMARLQFTRKPYTHWSISFLGDPELILDIESKYQGRQMQSNITNLISNQI 261
            ||||||:.|||||:||:||||||||||||||:||:.||::.||::|.:||||||||||:||||||
Mosquito   179 LGKKGSLALRVKQVSGLARLQFTRKPYTHWSLSFINDPKVELDVQSHFQGRQMQSNITSLISNQI 243

  Fly   262 RKAVRRKHTLPNYKLRYKPFFHWTAEEDASDCDIQPNGLLTVKLAELSRLMG-YPGASETYCTIT 325
            |||:|||||||||||||||||| ..|||....:|.|||.|.|.:||:|||.. ....:..|||:|
Mosquito   244 RKAIRRKHTLPNYKLRYKPFFH-RVEEDYELNEIVPNGSLEVTIAEISRLNAPIRTLTHVYCTLT 307

  Fly   326 LAPVPFIEASQRDSR--NVLISLDVFIHKAKNQQIGIVFKQSGSQVVRIESVLPNTPACKSNLLA 388
            ||.:|::.|.|:|.:  .:::|||:.|||||||||||||||| .|.|.|::|:|||||.|:.|..
Mosquito   308 LAHMPWVVARQQDDQGATMIVSLDIEIHKAKNQQIGIVFKQS-DQTVLIDAVIPNTPASKAELRR 371

  Fly   389 GDVLVAIEGRPVTTIQQIAKVVKTLQATVFSLRIERIIPGIIRNDAILEDFE-KYEDIGDLPSSY 452
            ||||::|:|:.||.|.|:.||:|||...:|.|||||::||.|||||:|:|:| ::|:|
Mosquito   372 GDVLLSIQGKRVTNISQVPKVIKTLNRPMFVLRIERLVPGQIRNDALLDDYEPEFEEI------- 429

  Fly   453 PCQPKL-----ETDEA-----ATADPTPKHLVVK---------PSLSGTPTNSP--KKSNLIAKA 496
              .|.|     :..||     .||....:.|..:         .|.|.||..:|  |.|.::...
Mosquito   430 --DPNLNITFVKNVEAVQIGGGTAVLRERKLARRNSKDNSGGESSHSNTPGTTPVKKSSTIVVGG 492

  Fly   497 IKKTMSRESGDKDRDKDKDKDKDKDKDKDKDKDKDKDKDKDKGKEEVEEPVNYFYQHSTIDCPFS 561
            .:.:..|.|..:.......|.|..:                         |..:.|||:||..|:
Mosquito   493 AETSTPRGSFSEPAAAGGPKPKALN-------------------------VECYPQHSSIDAEFN 532

  Fly   562 PLIHMEDVCSFQLDNSSRFLNVCVFGKSAGESVLLGYNNVQIGQILVECSETSLNQCLKQISLNP 626
            ..|.::|.|:|||.....:||:.|||||..|..||||.|:.|..|||||:|:.|...||:..|.|
Mosquito   533 SFIRLDDPCTFQLMEKYSYLNLSVFGKSNEEHRLLGYLNIPINSILVECNESHLGHHLKKYPLLP 597

  Fly   627 ASLQAVKTHPLSNQSGFNPNLCFGDILFGFSWMGNPNLTVGDVPIKSTSKSQSPARNPLAGDRVA 691
            .....|..||||.||||:.|.|:||:|..|.|.|:...::.. |..:|||:            ::
Mosquito   598 PEAIDVSNHPLSMQSGFDQNYCYGDVLLSFVWDGSALASLSS-PTAATSKA------------IS 649

  Fly   692 SEDQSQFLKLTS-----SMADSSTSG-------ESSSGTTAAP----RAHDFVRTHFHRATQCDF 740
            :|::.|.|...|     .:.|..|.|       .:||..|..|    :.|||:||||||.||||:
Mosquito   650 AENKKQRLITISRGSADKLDDDRTDGLPLDAKPSASSTFTQLPAQQQQQHDFIRTHFHRTTQCDY 714

  Fly   741 CGKKIWLKDAMQCQECSMCCHKKCIVKCQMATVCGPVD----------------CTGSIPATSST 789
            ||||||||||:||::|:||||||||.|||.:|||...:                .||.|.|..:.
Mosquito   715 CGKKIWLKDAVQCRDCAMCCHKKCINKCQSSTVCTANESSAGTASDRSSTTSSTSTGIIMAAGAA 779

  Fly   790 PSMAS----------RPEFTITQADNPQI-VDSSTGATPFDETSAASGGDQGQIQSP-------- 835
            .||||          :|||.:|:.::|.| |:        |....|....|.|:|..
Mosquito   780 ASMASTAAATVGTNQQPEFKVTEPESPTIEVE--------DFVDIAEEQQQQQLQQQQQQQQQQQ 836

  Fly   836 ------------TASGLDVHRSSLTGMLAQGIKR--QASNLDIPGIVSSLTGSGQQVNSKSLPPS 886
                        ..|.|:.||.|.:.:|.||:||  .|:||.||      |..|...:||||||:
Mosquito   837 QQQQQQQQQQIVPKSKLETHRQSFSDLLVQGLKRVNSANNLSIP------TMGGLNPSSKSLPPT 895

  Fly   887 PQHTPSRKSSIVEEATPALQQNPFESVTQHLEALPLDCPELSFEQVIVITEPIIRHTRNEDLMNL 951
            ||||| ||.|:..     :..|||..|||.||:||.|..||:.||::.:|.|:|.:..::.||.|
Mosquito   896 PQHTP-RKQSLAN-----VNANPFLLVTQRLESLPEDVNELNMEQIVDLTAPLIEYGPSDTLMAL 954

  Fly   952 AKSTSKLLYAALPPDERVAKINELLTKLKVALDAETEGYTLMNDAEKATES-------------- 1002
            |||:||.:|....||.|..|||:||:||.:|||.||...:::|..::::.|
Mosquito   955 AKSSSKAMYGDCEPDVRTEKINKLLSKLHIALDYETINQSVLNATKESSSSSSGSGAGANSKEIA 1019

  Fly  1003 --------------------SPWKSDRSDERVQALSIIMLYLCTGLQHAQG 1033
                                |.:.:.:|:|||||||||||:||:|||:.||
Mosquito  1020 DGKGKTPTQQQQQQQHDSTRSAFLAGQSEERVQALSIIMLHLCSGLQYVQG 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdzd8	NP_572771.1	SMP_PDZD8	94..282	CDD:439230	133/187 (71%)
		PDZ_6	371..424	CDD:436067	28/52 (54%)
		C1_PDZD8	722..775	CDD:410375	40/56 (71%)
		Herpes_BLLF1	<786..897	CDD:282904	46/143 (32%)
Pdzd8	XP_061519836.1	None