Protein Alignment HOXB5 and Ubx

DIOPT Version :9

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 105/325 - (32%)
• Similarity: 135/325 - (41%)
• Gaps: 100/325 - (30%)

Human     6 VNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVG 70
            ||.:...:..|..    |.|.|....|.  ...|..||..| |.||       .:|::::    |
  Fly    97 VNGYKDIWNTGGS----NGGGGGGGGGG--GGGAGGTGGAG-NANG-------GNAANAN----G 143

Human    71 ESSRAFPAPAQEPRFRQAASSCS--------LSSPESLPCTN-GDSHGAKPSASSPSDQATSASS 126
            :::.|...|.:       .|:|:        |.:....|.:: |.|.|...|.|..:..|....|
  Fly   144 QNNPAGGMPVR-------PSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVSGGNGNAGGVQS 201

Human   127 -----------SANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWM 180
                       :||.| |..|:|.:   .|||.|...|.....|. ||.:...||..|
  Fly   202 GVGVAGAGTAWNANCT-ISGAAAQT---AAASSLHQASNHTFYPW-MAIAGECPEDPT------- 254

Human   181 RKLHISHDMT--------------------------GPDG--KRARTAYTRYQTLELEKEFHFNR 217
             |..|..|:|                          |.:|  :|.|..||||||||||||||.|.
  Fly   255 -KSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNH 318

Human   218 YLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD--------------NKLKSMSLATAGSAFQ 268
            |||||||||:||||||:||||||||||||||.||:              ...|:.:.|.|.:|.|
  Fly   319 YLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKAAAAAAAAAAVQ 383

Human   269  268
              Fly   384  383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	29/123 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		28/115 (24%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeobox	198..251	CDD:395001	45/52 (87%)
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	45/52 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45659
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910