Protein Alignment HOXB5 and lab

DIOPT Version :10

• Sequence 1: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Sequence 2: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 79/314 - (25%)
• Similarity: 112/314 - (35%)
• Gaps: 118/314 - (37%)

Human    30 LSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGES--------SRAFPAPAQEPRFR 86
            |:|||...|....|.:.:.::|:         ...|.|.:..:        .:....|.|:|:..
  Fly   271 LAGSYALDAMDSLGMHAHMHHGL---------PHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHP 326

Human    87 QAASSCSLS-------SPESLPCTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEE 144
            |..|..:..       ||..  ..|....|...|..|.:..:||||:.|:              .
  Fly   327 QNQSPAAHQQHHQNSVSPNG--GMNRQQRGGVISPGSSTSSSTSASNGAH--------------P 375

Human   145 AASQLSSPSLARAQP--EPMATSTAAPEGQTPQI-FPWMRKLHISHDMTG--------------- 191
            |::|..||:.:.:.|  :.|......|:.|.|:: ...:..:| .:.|.|
  Fly   376 ASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMH-DYQMNGQLDMCRGGGGGGSGV 439

Human   192 --------------------------------------PDG---------------------KRA 197
                                                  |:|                     ...
  Fly   440 GNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSG 504

Human   198 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 251
            ||.:|..|..||||||||||||||.||||||:.|.|:|.|:||||||||||.||
  Fly   505 RTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKK 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	24/120 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		23/104 (22%)
		Antp-type hexapeptide	176..181		0/5 (0%)
		Homeodomain	195..251	CDD:459649	38/55 (69%)
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	38/52 (73%)