DRSC/TRiP Functional Genomics Resources

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Protein Alignment: HOXB5 and inv

Sequence 1:NP_002138.1 Gene:HOXB5 HGNCID:5116 Length:269 Species:Homo sapiens
Sequence 2:NP_523699.3 Gene:inv FlyBaseID:FBgn0001269 Length:576 Species:Drosophila melanogaster

Alignment Length:278 Identity:75/279 (27%)
Similarity:112/279 (40%) Gaps:88/279 (32%)


Human    23 NYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEP---R 84
            |.| |.|:|||          |.|.:.|..:.:.|||...:             |..:.:|   .
  Fly   302 NIG-GGSVSGS----------STGSSKNSGNTNGNRSPLKA-------------PKKSGKPLNLA 342

Human    85 FRQAASSCSLSSPESLP--CTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAAS 147
            ...||::.|||...||.  |:|          |:.|:...::||:.|        .|..|.:.  
  Fly   343 QSNAAANSSLSFSSSLANICSN----------SNDSNSTATSSSTTN--------TSGAPVDL-- 387

Human   148 QLSSPSLARAQPEPMATSTAAPEGQTPQIFP-WM--------------------RKLHISHDMTG 191
             :.||..|.......|:..:..:..||.::| |:                    :|...|....|
  Fly   388 -VKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAG 451

Human   192 -----------------PDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK 239
                             |:.||.|||::..|...|:.||:.|||||.:||.:::..|.|:|.|||
  Fly   452 GGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIK 516

Human   240 IWFQNRRMKWKKDNKLKS 257
            |||||:|.|.||.:..|:
  Fly   517 IWFQNKRAKLKKSSGTKN 534

Known Domains:


GeneSequenceDomainRegion External IDIdentity
HOXB5NP_002138.1 DNA_pol3_gamma3 <67..>171 CDD:331207 22/109 (20%)
Antp-type hexapeptide 176..181 2/26 (8%)
Homeobox 198..250 CDD:306543 27/52 (52%)
invNP_523699.3 Homeobox 474..527 CDD:278475 27/53 (51%)
Engrail_1_C_sig 529..554 CDD:287495 1/7 (14%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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